Search Results
Overview
| Uniprot ID | P01830 |
|---|---|
| Protein Name | Thy-1 membrane glycoprotein |
| Gene Name | Thy1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 60 | SLTREKKKHVLSGTL |
Function
May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain
Protein Sequence
10
MNPVISITLL
20
LSVLQMSRGQ
30
RVISLTACLV
40
NQNLRLDCRH
50
ENNTNLPIQH
60
EFSLTREKKK
70
HVLSGTLGVP
80
EHTYRSRVNL
90
FSDRFIKVLT
100
LANFTTKDEG
110
DYMCELRVSG
120
QNPTSSNKTI
130
NVIRDKLVKC
140
GGISLLVQNT
150
SWLLLLLLSL
160
SFLQATDFIS
L
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016324 | apical plasma membrane |
| Cellular Component | GO:0030673 | axolemma |
| Cellular Component | GO:0009986 | cell surface |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0032590 | dendrite membrane |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0009897 | external side of plasma membrane |
| Cellular Component | GO:0098978 | glutamatergic synapse |
| Cellular Component | GO:0030426 | growth cone |
| Cellular Component | GO:0045121 | membrane raft |
| Cellular Component | GO:0032809 | neuronal cell body membrane |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0098794 | postsynapse |
| Cellular Component | GO:0098793 | presynapse |
| Molecular Function | GO:0019899 | enzyme binding |
| Molecular Function | GO:0034235 | GPI anchor binding |
| Molecular Function | GO:0005096 | GTPase activator activity |
| Molecular Function | GO:0005178 | integrin binding |
| Molecular Function | GO:0019901 | protein kinase binding |
| Biological Process | GO:0001525 | angiogenesis |
| Biological Process | GO:0098609 | cell-cell adhesion |
| Biological Process | GO:0007267 | cell-cell signaling |
| Biological Process | GO:0007010 | cytoskeleton organization |
| Biological Process | GO:0048041 | focal adhesion assembly |
| Biological Process | GO:0034113 | heterotypic cell-cell adhesion |
| Biological Process | GO:0007229 | integrin-mediated signaling pathway |
| Biological Process | GO:0045576 | mast cell activation |
| Biological Process | GO:0043066 | negative regulation of apoptotic process |
| Biological Process | GO:0050771 | negative regulation of axonogenesis |
| Biological Process | GO:0030336 | negative regulation of cell migration |
| Biological Process | GO:0048147 | negative regulation of fibroblast proliferation |
| Biological Process | GO:0070571 | negative regulation of neuron projection regeneration |
| Biological Process | GO:0006469 | negative regulation of protein kinase activity |
| Biological Process | GO:0050860 | negative regulation of T cell receptor signaling pathway |
| Biological Process | GO:0002693 | positive regulation of cellular extravasation |
| Biological Process | GO:0051894 | positive regulation of focal adhesion assembly |
| Biological Process | GO:0043547 | positive regulation of GTPase activity |
| Biological Process | GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation |
| Biological Process | GO:0051281 | positive regulation of release of sequestered calcium ion into cytosol |
| Biological Process | GO:0050870 | positive regulation of T cell activation |
| Biological Process | GO:0046777 | protein autophosphorylation |
| Biological Process | GO:0043113 | receptor clustering |
| Biological Process | GO:0001952 | regulation of cell-matrix adhesion |
| Biological Process | GO:0048678 | response to axon injury |
| Biological Process | GO:0046549 | retinal cone cell development |
| Biological Process | GO:0050852 | T cell receptor signaling pathway |
Reference
[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.
[2] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.
[3] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.