Search Results
Overview
| Uniprot ID | P01946 |
|---|---|
| Protein Name | Hemoglobin subunit alpha-1/2 |
| Gene Name | Hba1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 12 | ADDKTNIKNCWGKIG |
| 17 | NIKNCWGKIGGHGGE |
| 57 | SPGSAQVKAHGKKVA |
| 62 | QVKAHGKKVADALAK |
| 69 | KVADALAKAADHVED |
| 8 | MVLSADDKTNIKNCW |
| 91 | LSDLHAHKLRVDPVN |
Function
Involved in oxygen transport from the lung to the various peripheral tissues
Protein Sequence
10
MVLSADDKTN
20
IKNCWGKIGG
30
HGGEYGEEAL
40
QRMFAAFPTT
50
KTYFSHIDVS
60
PGSAQVKAHG
70
KKVADALAKA
80
ADHVEDLPGA
90
LSTLSDLHAH
100
KLRVDPVNFK
110
FLSHCLLVTL
120
ACHHPGDFTP
130
AMHASLDKFL
140
ASVSTVLTSK
YR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0031838 | haptoglobin-hemoglobin complex |
| Cellular Component | GO:0005833 | hemoglobin complex |
| Molecular Function | GO:0001540 | amyloid-beta binding |
| Molecular Function | GO:0001664 | G protein-coupled receptor binding |
| Molecular Function | GO:0020037 | heme binding |
| Molecular Function | GO:0005506 | iron ion binding |
| Molecular Function | GO:0019825 | oxygen binding |
| Molecular Function | GO:0005344 | oxygen carrier activity |
| Biological Process | GO:0015670 | carbon dioxide transport |
| Biological Process | GO:0098869 | cellular oxidant detoxification |
| Biological Process | GO:0048821 | erythrocyte development |
| Biological Process | GO:0042744 | hydrogen peroxide catabolic process |
| Biological Process | GO:0006954 | inflammatory response |
| Biological Process | GO:0045776 | negative regulation of blood pressure |
| Biological Process | GO:0030185 | nitric oxide transport |
| Biological Process | GO:0015671 | oxygen transport |
| Biological Process | GO:0032355 | response to estradiol |
| Biological Process | GO:0042542 | response to hydrogen peroxide |
Reference
[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.