Search Results
Overview
| Uniprot ID | P02091 |
|---|---|
| Protein Name | Hemoglobin subunit beta-1 |
| Gene Name | Hbb |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 145 | VASALAHKYH***** |
| 60 | SAIMGNPKVKAHGKK |
| 67 | KVKAHGKKVINAFND |
| 77 | NAFNDGLKHLDNLKG |
| 83 | LKHLDNLKGTFAHLS |
| 9 | VHLTDAEKAAVNGLW |
| 96 | LSELHCDKLHVDPEN |
Function
Involved in oxygen transport from the lung to the various peripheral tissues
Protein Sequence
10
MVHLTDAEKA
20
AVNGLWGKVN
30
PDDVGGEALG
40
RLLVVYPWTQ
50
RYFDSFGDLS
60
SASAIMGNPK
70
VKAHGKKVIN
80
AFNDGLKHLD
90
NLKGTFAHLS
100
ELHCDKLHVD
110
PENFRLLGNM
120
IVIVLGHHLG
130
KEFTPCAQAA
140
FQKVVAGVAS
ALAHKYH
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0031838 | haptoglobin-hemoglobin complex |
| Cellular Component | GO:0005833 | hemoglobin complex |
| Molecular Function | GO:0020037 | heme binding |
| Molecular Function | GO:0031721 | hemoglobin alpha binding |
| Molecular Function | GO:0031722 | hemoglobin beta binding |
| Molecular Function | GO:0030492 | hemoglobin binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0019825 | oxygen binding |
| Molecular Function | GO:0005344 | oxygen carrier activity |
| Molecular Function | GO:0044877 | protein-containing complex binding |
| Biological Process | GO:0015670 | carbon dioxide transport |
| Biological Process | GO:0098869 | cellular oxidant detoxification |
| Biological Process | GO:0048821 | erythrocyte development |
| Biological Process | GO:0006749 | glutathione metabolic process |
| Biological Process | GO:0030097 | hemopoiesis |
| Biological Process | GO:0042744 | hydrogen peroxide catabolic process |
| Biological Process | GO:0006954 | inflammatory response |
| Biological Process | GO:0030185 | nitric oxide transport |
| Biological Process | GO:0015671 | oxygen transport |
| Biological Process | GO:0010999 | regulation of eIF2 alpha phosphorylation by heme |
| Biological Process | GO:0070293 | renal absorption |
| Biological Process | GO:0042542 | response to hydrogen peroxide |
Reference
[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.