Search Results
Overview
| Uniprot ID | P02276 |
|---|---|
| Protein Name | Histone H2A.2.1 |
| Gene Name | - |
| Organism | Triticum aestivum |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 24 | PRKKSVTKSIKAGLQ |
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
Protein Sequence
10
MDGSKAKKVA
20
AKKFGGPRKK
30
SVTKSIKAGL
40
QFPVGRIGRY
50
LKKGRYAQRV
60
GSGAPVYLAA
70
VLEYLAAEVL
80
ELAGNAAKDN
90
KKTRIVPRHL
100
LLAIRNDQEL
110
GRLLSGVTIA
120
HGGVIPNINP
130
VLLPKKAAEK
140
AEKAGAAPKS
150
PKKTTKSPKK
A
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000792 | heterochromatin |
| Cellular Component | GO:0000786 | nucleosome |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003682 | chromatin binding |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:0030527 | structural constituent of chromatin |
| Biological Process | GO:0031507 | heterochromatin formation |
Reference
[1] Zhu J, Guo W, Lan Y. Global Analysis of Lysine Lactylation of Germinated Seeds in Wheat.. Int J Mol Sci 24(22). 2023 Nov 11. PMID: 38003390.