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Overview

Uniprot IDP02401
Protein NameLarge ribosomal subunit protein P2
Gene NameRplp2
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
25 PSAKDIKKILDSVGI

Function

Plays an important role in the elongation step of protein synthesis

Protein Sequence

10 MRYVASYLLA 20 ALGGNSNPSA 30 KDIKKILDSV 40 GIEADDERLN 50 KVISELNGKN 60 IEDVIAQGVG 70 KLASVPAGGA 80 VAVSAAPGSA 90 APAAGSAPAA 100 AEEKKDEKKE 110 ESEESDDDMG FGLFD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0022625 cytosolic large ribosomal subunit
Cellular Component GO:0045202 synapse
Molecular Function GO:0005506 iron ion binding
Molecular Function GO:0043021 ribonucleoprotein complex binding
Molecular Function GO:0003735 structural constituent of ribosome
Biological Process GO:0071320 cellular response to cAMP
Biological Process GO:1904401 cellular response to Thyroid stimulating hormone
Biological Process GO:0002181 cytoplasmic translation
Biological Process GO:0002182 cytoplasmic translational elongation
Biological Process GO:0045727 positive regulation of translation

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.