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Overview

Uniprot IDP02625
Protein NameParvalbumin alpha
Gene NamePvalb
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
14 LSAEDIKKAIGAFTA
46 KSADDVKKVFHILDK
53 KVFHILDKDKSGFIE

Function

In muscle, parvalbumin is thought to be involved in relaxation after contraction (By similarity). It binds two calcium ions (PubMed:19622856, PubMed:16101280, PubMed:15169955, PubMed:15287728, PubMed:11562941, PubMed:8289291)

Protein Sequence

10 MSMTDLLSAE 20 DIKKAIGAFT 30 AADSFDHKKF 40 FQMVGLKKKS 50 ADDVKKVFHI 60 LDKDKSGFIE 70 EDELGSILKG 80 FSSDARDLSA 90 KETKTLMAAG 100 DKDGDGKIGV 110 EEFSTLVAES

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030424 axon
Cellular Component GO:0032437 cuticular plate
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0043025 neuronal cell body
Cellular Component GO:0032991 protein-containing complex
Cellular Component GO:0032420 stereocilium
Cellular Component GO:0043195 terminal bouton
Molecular Function GO:0005509 calcium ion binding
Molecular Function GO:0042802 identical protein binding
Molecular Function GO:0044877 protein-containing complex binding
Biological Process GO:0090102 cochlea development
Biological Process GO:0098976 excitatory chemical synaptic transmission
Biological Process GO:0010467 gene expression
Biological Process GO:0098977 inhibitory chemical synaptic transmission

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.