Search Results
Overview
| Uniprot ID | P02766 |
|---|---|
| Protein Name | Transthyretin |
| Gene Name | TTR |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 35 | SKCPLMVKVLDAVRG |
| 55 | VAVHVFRKAADDTWE |
| 96 | YKVEIDTKSYWKALG |
Function
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain
Protein Sequence
10
MASHRLLLLC
20
LAGLVFVSEA
30
GPTGTGESKC
40
PLMVKVLDAV
50
RGSPAINVAV
60
HVFRKAADDT
70
WEPFASGKTS
80
ESGELHGLTT
90
EEEFVEGIYK
100
VEIDTKSYWK
110
ALGISPFHEH
120
AEVVFTANDS
130
GPRRYTIAAL
140
LSPYSYSTTA
VVTNPKE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0035578 | azurophil granule lumen |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0032991 | protein-containing complex |
| Molecular Function | GO:0005179 | hormone activity |
| Molecular Function | GO:0042562 | hormone binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0140313 | molecular sequestering activity |
| Molecular Function | GO:0044877 | protein-containing complex binding |
| Biological Process | GO:0006144 | purine nucleobase metabolic process |
| Biological Process | GO:0001523 | retinoid metabolic process |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] Lin Y, Chen M, Wang D, Yu Y, Chen R et al.. Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.. J Proteome Res 22(6):1712-1722. 2023 Jun 2. PMID: 37159428.