Search Results
Overview
| Uniprot ID | P04117 |
|---|---|
| Protein Name | Fatty acid-binding protein, adipocyte |
| Gene Name | Fabp4 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 121 | LVVECVMKGVTSTRV |
| 59 | IRSESTFKNTEISFK |
Function
Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus
Protein Sequence
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005811 | lipid droplet |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0005504 | fatty acid binding |
| Molecular Function | GO:0051427 | hormone receptor binding |
| Molecular Function | GO:0060229 | lipase activator activity |
| Molecular Function | GO:0036041 | long-chain fatty acid binding |
| Molecular Function | GO:0005324 | long-chain fatty acid transmembrane transporter activity |
| Biological Process | GO:0050873 | brown fat cell differentiation |
| Biological Process | GO:0071285 | cellular response to lithium ion |
| Biological Process | GO:0071356 | cellular response to tumor necrosis factor |
| Biological Process | GO:0042632 | cholesterol homeostasis |
| Biological Process | GO:0006631 | fatty acid metabolic process |
| Biological Process | GO:0015908 | fatty acid transport |
| Biological Process | GO:0140042 | lipid droplet formation |
| Biological Process | GO:0015909 | long-chain fatty acid transport |
| Biological Process | GO:0045892 | negative regulation of DNA-templated transcription |
| Biological Process | GO:0006469 | negative regulation of protein kinase activity |
| Biological Process | GO:0008284 | positive regulation of cell population proliferation |
| Biological Process | GO:0120162 | positive regulation of cold-induced thermogenesis |
| Biological Process | GO:0050729 | positive regulation of inflammatory response |
| Biological Process | GO:0009617 | response to bacterium |
| Biological Process | GO:0019433 | triglyceride catabolic process |
| Biological Process | GO:0050872 | white fat cell differentiation |
Reference
[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.
[2] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.
[3] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.