Search Results
Overview
| Uniprot ID | P04178 |
|---|---|
| Protein Name | Superoxide dismutase [Cu-Zn] |
| Gene Name | SOD1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 122 | RTMVVHEKPDDLGRG |
| 136 | GGNEESTKTGNAGSR |
| 27 | YFELKGEKTVLVTGT |
| 4 | ****MATKAVCVLKG |
| 75 | SKKHGGPKDQERHVG |
Function
Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Catalyzes the oxidation of hydrogen sulfide (H2S) to sulfate, playing an important role in detoxifying H2S and limiting the accumulation of reactive sulfur species (RSS) such as persulfides and polysulfides
Protein Sequence
10
MATKAVCVLK
20
GDGPVQGTIY
30
FELKGEKTVL
40
VTGTIKGLAE
50
GDHGFHVHQF
60
GDNTQGCTSA
70
GPHFNPESKK
80
HGGPKDQERH
90
VGDLGNVTAG
100
KDGVATVYIE
110
DSVIALSGDH
120
SIIGRTMVVH
130
EKPDDLGRGG
140
NEESTKTGNA
150
GSRLACGVIG
ITQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0031410 | cytoplasmic vesicle |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0032839 | dendrite cytoplasm |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0043025 | neuronal cell body |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005777 | peroxisome |
| Cellular Component | GO:0032991 | protein-containing complex |
| Molecular Function | GO:0005507 | copper ion binding |
| Molecular Function | GO:0030346 | protein phosphatase 2B binding |
| Molecular Function | GO:0051087 | protein-folding chaperone binding |
| Molecular Function | GO:0004784 | superoxide dismutase activity |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0060088 | auditory receptor cell stereocilium organization |
| Biological Process | GO:0007566 | embryo implantation |
| Biological Process | GO:0006749 | glutathione metabolic process |
| Biological Process | GO:0060047 | heart contraction |
| Biological Process | GO:0050665 | hydrogen peroxide biosynthetic process |
| Biological Process | GO:0006879 | intracellular iron ion homeostasis |
| Biological Process | GO:0007626 | locomotory behavior |
| Biological Process | GO:0046716 | muscle cell cellular homeostasis |
| Biological Process | GO:0002262 | myeloid cell homeostasis |
| Biological Process | GO:0043524 | negative regulation of neuron apoptotic process |
| Biological Process | GO:0060052 | neurofilament cytoskeleton organization |
| Biological Process | GO:0001541 | ovarian follicle development |
| Biological Process | GO:0032287 | peripheral nervous system myelin maintenance |
| Biological Process | GO:0001819 | positive regulation of cytokine production |
| Biological Process | GO:0043410 | positive regulation of MAPK cascade |
| Biological Process | GO:0072593 | reactive oxygen species metabolic process |
| Biological Process | GO:0008217 | regulation of blood pressure |
| Biological Process | GO:0051881 | regulation of mitochondrial membrane potential |
| Biological Process | GO:0040014 | regulation of multicellular organism growth |
| Biological Process | GO:0060087 | relaxation of vascular associated smooth muscle |
| Biological Process | GO:0019430 | removal of superoxide radicals |
| Biological Process | GO:0048678 | response to axon injury |
| Biological Process | GO:0045471 | response to ethanol |
| Biological Process | GO:0009408 | response to heat |
| Biological Process | GO:0042542 | response to hydrogen peroxide |
| Biological Process | GO:0000303 | response to superoxide |
| Biological Process | GO:0001895 | retina homeostasis |
| Biological Process | GO:0007605 | sensory perception of sound |
| Biological Process | GO:0007283 | spermatogenesis |
| Biological Process | GO:0006801 | superoxide metabolic process |
| Biological Process | GO:0019226 | transmission of nerve impulse |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.