Search Results
Overview
| Uniprot ID | P04216 |
|---|---|
| Protein Name | Thy-1 membrane glycoprotein |
| Gene Name | THY1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 60 | SLTRETKKHVLFGTV |
Function
May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain
Protein Sequence
10
MNLAISIALL
20
LTVLQVSRGQ
30
KVTSLTACLV
40
DQSLRLDCRH
50
ENTSSSPIQY
60
EFSLTRETKK
70
HVLFGTVGVP
80
EHTYRSRTNF
90
TSKYNMKVLY
100
LSAFTSKDEG
110
TYTCALHHSG
120
HSPPISSQNV
130
TVLRDKLVKC
140
EGISLLAQNT
150
SWLLLLLLSL
160
SLLQATDFMS
L
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016324 | apical plasma membrane |
| Cellular Component | GO:0030673 | axolemma |
| Cellular Component | GO:0009986 | cell surface |
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0032590 | dendrite membrane |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0009897 | external side of plasma membrane |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0005925 | focal adhesion |
| Cellular Component | GO:0098978 | glutamatergic synapse |
| Cellular Component | GO:0030426 | growth cone |
| Cellular Component | GO:0045121 | membrane raft |
| Cellular Component | GO:0032809 | neuronal cell body membrane |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0098794 | postsynapse |
| Cellular Component | GO:0098793 | presynapse |
| Molecular Function | GO:0034235 | GPI anchor binding |
| Molecular Function | GO:0005096 | GTPase activator activity |
| Molecular Function | GO:0005178 | integrin binding |
| Biological Process | GO:0001525 | angiogenesis |
| Biological Process | GO:0098609 | cell-cell adhesion |
| Biological Process | GO:0007267 | cell-cell signaling |
| Biological Process | GO:0007010 | cytoskeleton organization |
| Biological Process | GO:0048041 | focal adhesion assembly |
| Biological Process | GO:0034113 | heterotypic cell-cell adhesion |
| Biological Process | GO:0007229 | integrin-mediated signaling pathway |
| Biological Process | GO:0050771 | negative regulation of axonogenesis |
| Biological Process | GO:0030336 | negative regulation of cell migration |
| Biological Process | GO:0070571 | negative regulation of neuron projection regeneration |
| Biological Process | GO:0006469 | negative regulation of protein kinase activity |
| Biological Process | GO:0050860 | negative regulation of T cell receptor signaling pathway |
| Biological Process | GO:0002693 | positive regulation of cellular extravasation |
| Biological Process | GO:0051894 | positive regulation of focal adhesion assembly |
| Biological Process | GO:0043547 | positive regulation of GTPase activity |
| Biological Process | GO:0051281 | positive regulation of release of sequestered calcium ion into cytosol |
| Biological Process | GO:0050870 | positive regulation of T cell activation |
| Biological Process | GO:0043113 | receptor clustering |
| Biological Process | GO:0001952 | regulation of cell-matrix adhesion |
| Biological Process | GO:0046549 | retinal cone cell development |
| Biological Process | GO:0050852 | T cell receptor signaling pathway |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.