Search Results
Overview
| Uniprot ID | P05063 |
|---|---|
| Protein Name | Fructose-bisphosphate aldolase C |
| Gene Name | Aldoc |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 42 | ESVGSMAKRLSQIGV |
Function
Catalyzes the reversible conversion of beta-D-fructose 1,6-bisphosphate (FBP) into two triose phosphate and plays a key role in glycolysis and gluconeogenesis
Protein Sequence
10
MPHSYPALSA
20
EQKKELSDIA
30
LRIVTPGKGI
40
LAADESVGSM
50
AKRLSQIGVE
60
NTEENRRLYR
70
QVLFSADDRV
80
KKCIGGVIFF
90
HETLYQKDDN
100
GVPFVRTIQD
110
KGILVGIKVD
120
KGVVPLAGTD
130
GETTTQGLDG
140
LLERCAQYKK
150
DGADFAKWRC
160
VLKISDRTPS
170
ALAILENANV
180
LARYASICQQ
190
NGIVPIVEPE
200
ILPDGDHDLK
210
RCQYVTEKVL
220
AAVYKALSDH
230
HVYLEGTLLK
240
PNMVTPGHAC
250
PIKYSPEEIA
260
MATVTALRRT
270
VPPAVPGVTF
280
LSGGQSEEEA
290
SLNLNAINRC
300
PLPRPWALTF
310
SYGRALQASA
320
LNAWRGQRDN
330
AGAATEEFIK
340
RAEMNGLAAQ
350
GRYEGSGDGG
360
AAAQSLYIAN
HAY
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0099524 | postsynaptic cytosol |
| Molecular Function | GO:0008092 | cytoskeletal protein binding |
| Molecular Function | GO:0004332 | fructose-bisphosphate aldolase activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0044877 | protein-containing complex binding |
| Biological Process | GO:0030855 | epithelial cell differentiation |
| Biological Process | GO:0030388 | fructose 1,6-bisphosphate metabolic process |
| Biological Process | GO:0006094 | gluconeogenesis |
| Biological Process | GO:0006096 | glycolytic process |
Reference
[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.
[2] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.