Search Results
Overview
| Uniprot ID | P05090 |
|---|---|
| Protein Name | Apolipoprotein D |
| Gene Name | APOD |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 176 | SNNIDVKKMTVTDQV |
| 75 | LMENGKIKVLNQELR |
Function
APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts
Protein Sequence
10
MVMLLLLLSA
20
LAGLFGAAEG
30
QAFHLGKCPN
40
PPVQENFDVN
50
KYLGRWYEIE
60
KIPTTFENGR
70
CIQANYSLME
80
NGKIKVLNQE
90
LRADGTVNQI
100
EGEATPVNLT
110
EPAKLEVKFS
120
WFMPSAPYWI
130
LATDYENYAL
140
VYSCTCIIQL
150
FHVDFAWILA
160
RNPNLPPETV
170
DSLKNILTSN
180
NIDVKKMTVT
DQVNCPKLS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0022626 | cytosolic ribosome |
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0043025 | neuronal cell body |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Molecular Function | GO:0015485 | cholesterol binding |
| Molecular Function | GO:0005319 | lipid transporter activity |
| Biological Process | GO:0001525 | angiogenesis |
| Biological Process | GO:0007420 | brain development |
| Biological Process | GO:0006006 | glucose metabolic process |
| Biological Process | GO:0006629 | lipid metabolic process |
| Biological Process | GO:1900016 | negative regulation of cytokine production involved in inflammatory response |
| Biological Process | GO:0051895 | negative regulation of focal adhesion assembly |
| Biological Process | GO:0060588 | negative regulation of lipoprotein lipid oxidation |
| Biological Process | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production |
| Biological Process | GO:0010642 | negative regulation of platelet-derived growth factor receptor signaling pathway |
| Biological Process | GO:0042308 | negative regulation of protein import into nucleus |
| Biological Process | GO:0048662 | negative regulation of smooth muscle cell proliferation |
| Biological Process | GO:2000098 | negative regulation of smooth muscle cell-matrix adhesion |
| Biological Process | GO:2000405 | negative regulation of T cell migration |
| Biological Process | GO:0014012 | peripheral nervous system axon regeneration |
| Biological Process | GO:0048678 | response to axon injury |
| Biological Process | GO:0000302 | response to reactive oxygen species |
| Biological Process | GO:0042246 | tissue regeneration |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.