Search Results

Overview

Uniprot IDP05621
Protein NameHistone H2B.2
Gene Name-
OrganismTriticum aestivum

Kla Sites from experimental identification

Position Flanking peptide
11 KKPAAENKVEKAAEK

Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling

Protein Sequence

10 MPBKKPAAEN 20 KVEKAAEKTP 30 AGKKPKAEKR 40 LPAGKTASKE 50 AGGEGKTRGR 60 KKGSKAKKGV 70 ETYKIYIFKV 80 LKQVHPDIGI 90 SSKAMSIMNS 100 FINDIFEKLA 110 GESAKLARYN 120 KKPTITSREI 130 QTSVRLVLPG 140 ELAKHAVSEG 150 TKAVTKFTSS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0000786 nucleosome
Cellular Component GO:0005634 nucleus
Molecular Function GO:0003677 DNA binding
Molecular Function GO:0046982 protein heterodimerization activity
Molecular Function GO:0030527 structural constituent of chromatin
Biological Process GO:0006325 chromatin organization

Reference

[1] Zhu J, Guo W, Lan Y. Global Analysis of Lysine Lactylation of Germinated Seeds in Wheat.. Int J Mol Sci 24(22). 2023 Nov 11. PMID: 38003390.