Search Results
Overview
| Uniprot ID | P05976 |
|---|---|
| Protein Name | Myosin light chain 1/3, skeletal muscle isoform |
| Gene Name | MYL1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 106 | SNEELNAKKIEFEQF |
| 162 | VLATLGEKMKEEEVE |
| 32 | APAPAPAKPKEEKID |
| 34 | APAPAKPKEEKIDLS |
| 37 | PAKPKEEKIDLSAIK |
| 93 | PTNAEVRKVLGNPSN |
Function
Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function
Protein Sequence
10
MAPKKDVKKP
20
VAAAAAAPAP
30
APAPAPAPAP
40
AKPKEEKIDL
50
SAIKIEFSKE
60
QQDEFKEAFL
70
LFDRTGDSKI
80
TLSQVGDVLR
90
ALGTNPTNAE
100
VRKVLGNPSN
110
EELNAKKIEF
120
EQFLPMMQAI
130
SNNKDQATYE
140
DFVEGLRVFD
150
KEGNGTVMGA
160
ELRHVLATLG
170
EKMKEEEVEA
180
LMAGQEDSNG
190
CINYEAFVKH
IMSI
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0043292 | contractile muscle fiber |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005859 | muscle myosin complex |
| Cellular Component | GO:0030016 | myofibril |
| Cellular Component | GO:0016460 | myosin II complex |
| Cellular Component | GO:0030017 | sarcomere |
| Molecular Function | GO:0005509 | calcium ion binding |
| Molecular Function | GO:0000146 | microfilament motor activity |
| Molecular Function | GO:0008307 | structural constituent of muscle |
| Biological Process | GO:0006936 | muscle contraction |
| Biological Process | GO:0030049 | muscle filament sliding |
Reference
[1] Lin Y, Chen M, Wang D, Yu Y, Chen R et al.. Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.. J Proteome Res 22(6):1712-1722. 2023 Jun 2. PMID: 37159428.