Search Results
Overview
| Uniprot ID | P05977 |
|---|---|
| Protein Name | Myosin light chain 1/3, skeletal muscle isoform |
| Gene Name | Myl1 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 100 | SNEEMNAKKIEFEQF |
| 156 | VLATLGEKMKEEEVE |
| 26 | APAPAPAKPKEEKID |
| 28 | APAPAKPKEEKIDLS |
| 31 | PAKPKEEKIDLSAIK |
| 38 | KIDLSAIKIEFSKEQ |
| 43 | AIKIEFSKEQQEDFK |
| 50 | KEQQEDFKEAFLLFD |
| 63 | FDRTGECKITLSQVG |
| 8 | MAPKKDVKKPAAAPA |
| 86 | NPTNAEVKKVLGNPS |
| 87 | PTNAEVKKVLGNPSN |
| 9 | APKKDVKKPAAAPAP |
Function
Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function
Protein Sequence
10
MAPKKDVKKP
20
AAAPAPAPAP
30
APAPAKPKEE
40
KIDLSAIKIE
50
FSKEQQEDFK
60
EAFLLFDRTG
70
ECKITLSQVG
80
DVLRALGTNP
90
TNAEVKKVLG
100
NPSNEEMNAK
110
KIEFEQFLPM
120
MQAISNNKDQ
130
GGYEDFVEGL
140
RVFDKEGNGT
150
VMGAELRHVL
160
ATLGEKMKEE
170
EVEALLAGQE
180
DSNGCINYEA
FVKHIMSV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0043292 | contractile muscle fiber |
| Cellular Component | GO:0030016 | myofibril |
| Cellular Component | GO:0016460 | myosin II complex |
| Cellular Component | GO:0016461 | unconventional myosin complex |
| Molecular Function | GO:0005509 | calcium ion binding |
| Molecular Function | GO:0000146 | microfilament motor activity |
| Molecular Function | GO:0008307 | structural constituent of muscle |
| Biological Process | GO:0060048 | cardiac muscle contraction |
| Biological Process | GO:0006936 | muscle contraction |
| Biological Process | GO:0030049 | muscle filament sliding |
Reference
[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.