Search Results
Overview
| Uniprot ID | P06302 |
|---|---|
| Protein Name | Prothymosin alpha |
| Gene Name | Ptma |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 103 | EDDDVETKKQKKTDE |
| 15 | TSSEITTKDLKEKKE |
Function
Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections
Protein Sequence
10
MSDAAVDTSS
20
EITTKDLKEK
30
KEVVEEAENG
40
RDAPANGNAQ
50
NEENGEQEAD
60
NEVDEEEEEG
70
GEEEEEEEEG
80
DGEEEDGDED
90
EEAEAPTGKR
100
VAEDDEDDDV
110
ETKKQKKTDE
DD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0005509 | calcium ion binding |
| Molecular Function | GO:0140297 | DNA-binding transcription factor binding |
| Molecular Function | GO:0042393 | histone binding |
| Molecular Function | GO:0140713 | histone chaperone activity |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:0006325 | chromatin organization |
| Biological Process | GO:0043066 | negative regulation of apoptotic process |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.