Search Results
Overview
| Uniprot ID | P06732 |
|---|---|
| Protein Name | Creatine kinase M-type |
| Gene Name | CKM |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 101 | SDRHGGYKPTDKHKT |
| 266 | KIEEIFKKAGHPFMW |
| 307 | AHLSKHPKFEEILTR |
Function
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa
Protein Sequence
10
MPFGNTHNKF
20
KLNYKPEEEY
30
PDLSKHNNHM
40
AKVLTLELYK
50
KLRDKETPSG
60
FTVDDVIQTG
70
VDNPGHPFIM
80
TVGCVAGDEE
90
SYEVFKELFD
100
PIISDRHGGY
110
KPTDKHKTDL
120
NHENLKGGDD
130
LDPNYVLSSR
140
VRTGRSIKGY
150
TLPPHCSRGE
160
RRAVEKLSVE
170
ALNSLTGEFK
180
GKYYPLKSMT
190
EKEQQQLIDD
200
HFLFDKPVSP
210
LLLASGMARD
220
WPDARGIWHN
230
DNKSFLVWVN
240
EEDHLRVISM
250
EKGGNMKEVF
260
RRFCVGLQKI
270
EEIFKKAGHP
280
FMWNQHLGYV
290
LTCPSNLGTG
300
LRGGVHVKLA
310
HLSKHPKFEE
320
ILTRLRLQKR
330
GTGGVDTAAV
340
GSVFDVSNAD
350
RLGSSEVEQV
360
QLVVDGVKLM
370
VEMEKKLEKG
380
QSIDDMIPAQ
K
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005615 | extracellular space |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0004111 | creatine kinase activity |
| Biological Process | GO:0046314 | phosphocreatine biosynthetic process |
Reference
[1] Lin Y, Chen M, Wang D, Yu Y, Chen R et al.. Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.. J Proteome Res 22(6):1712-1722. 2023 Jun 2. PMID: 37159428.