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Overview

Uniprot IDP07171
Protein NameCalbindin
Gene NameCalb1
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
223 KDLCEKNKQELDINN
236 NNISTYKKNIMALSD
246 MALSDGGKLYRTDLA

Function

Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase

Protein Sequence

10 MAESHLQSSL 20 ITASQFFEIW 30 LHFDADGSGY 40 LEGKELQNLI 50 QELLQARKKA 60 GLELSPEMKT 70 FVDQYGQRDD 80 GKIGIVELAH 90 VLPTEENFLL 100 LFRCQQLKSC 110 EEFMKTWRKY 120 DTDHSGFIET 130 EELKNFLKDL 140 LEKANKTVDD 150 TKLAEYTDLM 160 LKLFDSNNDG 170 KLELTEMARL 180 LPVQENFLLK 190 FQGIKMCGKE 200 FNKAFELYDQ 210 DGNGYIDENE 220 LDALLKDLCE 230 KNKQELDINN 240 ISTYKKNIMA 250 LSDGGKLYRT 260 DLALILSAGD N

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030424 axon
Cellular Component GO:0044305 calyx of Held
Cellular Component GO:0044297 cell body
Cellular Component GO:0032437 cuticular plate
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0030425 dendrite
Cellular Component GO:0098982 GABA-ergic synapse
Cellular Component GO:0098978 glutamatergic synapse
Cellular Component GO:0098686 hippocampal mossy fiber to CA3 synapse
Cellular Component GO:0043005 neuron projection
Cellular Component GO:0043025 neuronal cell body
Cellular Component GO:0005634 nucleus
Cellular Component GO:0098794 postsynapse
Cellular Component GO:0099524 postsynaptic cytosol
Cellular Component GO:0099523 presynaptic cytosol
Cellular Component GO:0032420 stereocilium
Cellular Component GO:0045202 synapse
Cellular Component GO:0043195 terminal bouton
Molecular Function GO:0005509 calcium ion binding
Molecular Function GO:0099567 calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration
Molecular Function GO:0099534 calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration
Molecular Function GO:0005499 vitamin D binding
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0090102 cochlea development
Biological Process GO:0007611 learning or memory
Biological Process GO:0007626 locomotory behavior
Biological Process GO:0007616 long-term memory
Biological Process GO:0072205 metanephric collecting duct development
Biological Process GO:0072286 metanephric connecting tubule development
Biological Process GO:0072221 metanephric distal convoluted tubule development
Biological Process GO:0035502 metanephric part of ureteric bud development
Biological Process GO:0048167 regulation of synaptic plasticity
Biological Process GO:0010996 response to auditory stimulus
Biological Process GO:0060041 retina development in camera-type eye
Biological Process GO:0010842 retina layer formation
Biological Process GO:0007614 short-term memory
Biological Process GO:0042359 vitamin D metabolic process

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.