Search Results
Overview
| Uniprot ID | P07988 |
|---|---|
| Protein Name | Pulmonary surfactant-associated protein B |
| Gene Name | SFTPB |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 106 | ECNVLPLKLLMPQCN |
Function
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter
Protein Sequence
10
MAESHLLQWL
20
LLLLPTLCGP
30
GTAAWTTSSL
40
ACAQGPEFWC
50
QSLEQALQCR
60
ALGHCLQEVW
70
GHVGADDLCQ
80
ECEDIVHILN
90
KMAKEAIFQD
100
TMRKFLEQEC
110
NVLPLKLLMP
120
QCNQVLDDYF
130
PLVIDYFQNQ
140
TDSNGICMHL
150
GLCKSRQPEP
160
EQEPGMSDPL
170
PKPLRDPLPD
180
PLLDKLVLPV
190
LPGALQARPG
200
PHTQDLSEQQ
210
FPIPLPYCWL
220
CRALIKRIQA
230
MIPKGALAVA
240
VAQVCRVVPL
250
VAGGICQCLA
260
ERYSVILLDT
270
LLGRMLPQLV
280
CRLVLRCSMD
290
DSAGPRSPTG
300
EWLPRDSECH
310
LCMSVTTQAG
320
NSSEQAIPQA
330
MLQACVGSWL
340
DREKCKQFVE
350
QHTPQLLTLV
360
PRGWDAHTTC
370
QALGVCGTMS
380
SPLQCIHSPD
L
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0097208 | alveolar lamellar body |
| Cellular Component | GO:0045334 | clathrin-coated endocytic vesicle |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0042599 | lamellar body |
| Cellular Component | GO:0005764 | lysosome |
| Cellular Component | GO:0005771 | multivesicular body |
| Cellular Component | GO:0097486 | multivesicular body lumen |
| Biological Process | GO:0009887 | animal organ morphogenesis |
| Biological Process | GO:0007585 | respiratory gaseous exchange by respiratory system |
| Biological Process | GO:0006665 | sphingolipid metabolic process |
Reference
[1] Yan M, Tu H, Tang S, Gai Z, Shi Q et al.. Lactylated Proteomic Analysis Reveals Functional Implications of Lysine Lactylation In Asthenozoospermia.. Mol Cell Proteomics 24(12):101439. 2025 Dec. PMID: 41192556.