Search Results
Overview
| Uniprot ID | P08074 |
|---|---|
| Protein Name | Carbonyl reductase [NADPH] 2 |
| Gene Name | Cbr2 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 2 | ******MKLNFSGLR |
Function
May function in the pulmonary metabolism of endogenous carbonyl compounds, such as aliphatic aldehydes and ketones derived from lipid peroxidation, 3-ketosteroids and fatty aldehydes, as well as in xenobiotic metabolism
Protein Sequence
10
MKLNFSGLRA
20
LVTGAGKGIG
30
RDTVKALHAS
40
GAKVVAVTRT
50
NSDLVSLAKE
60
CPGIEPVCVD
70
LGDWDATEKA
80
LGGIGPVDLL
90
VNNAALVIMQ
100
PFLEVTKEAF
110
DRSFSVNLRS
120
VFQVSQMVAR
130
DMINRGVPGS
140
IVNVSSMVAH
150
VTFPNLITYS
160
STKGAMTMLT
170
KAMAMELGPH
180
KIRVNSVNPT
190
VVLTDMGKKV
200
SADPEFARKL
210
KERHPLRKFA
220
EVEDVVNSIL
230
FLLSDRSAST
240
SGGGILVDAG
YLAS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005759 | mitochondrial matrix |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0004090 | carbonyl reductase (NADPH) activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0050038 | L-xylulose reductase (NADPH) activity |
| Biological Process | GO:0006006 | glucose metabolic process |
| Biological Process | GO:0005997 | xylulose metabolic process |
Reference
[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.