Search Results
Overview
| Uniprot ID | P08081 |
|---|---|
| Protein Name | Clathrin light chain A |
| Gene Name | Clta |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 130 | ALDANSRKQEAEWKE |
| 136 | RKQEAEWKEKAVKEL |
| 141 | EWKEKAVKELEEWYA |
| 156 | RQDEQLQKTKASNRV |
| 223 | RLCDFNPKSSKQAKD |
Function
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Acts as a component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge (By similarity)
Protein Sequence
10
MAELDPFGAP
20
AGAPGGPALG
30
NGVAGAGEED
40
PAAAFLAQQE
50
SEIAGIENDE
60
AFAILDGGAP
70
GPQAHGEPPG
80
GPDAVDGVMN
90
GEYYQESNGP
100
TDSYAAISEV
110
DRLQSEPESI
120
RKWREEQTER
130
LEALDANSRK
140
QEAEWKEKAV
150
KELEEWYARQ
160
DEQLQKTKAS
170
NRVADEAFYK
180
QPFADVIGYV
190
TNINHPCYSL
200
EQAAEEAFVN
210
DIDESSPGTE
220
WERVARLCDF
230
NPKSSKQAKD
240
VSRMRSVLIS
LKQAPLVH
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030125 | clathrin vesicle coat |
| Cellular Component | GO:0030118 | clathrin coat |
| Cellular Component | GO:0030132 | clathrin coat of coated pit |
| Cellular Component | GO:0030130 | clathrin coat of trans-Golgi network vesicle |
| Cellular Component | GO:0071439 | clathrin complex |
| Cellular Component | GO:0030669 | clathrin-coated endocytic vesicle membrane |
| Cellular Component | GO:0005905 | clathrin-coated pit |
| Cellular Component | GO:0030136 | clathrin-coated vesicle |
| Cellular Component | GO:0031410 | cytoplasmic vesicle |
| Cellular Component | GO:0005768 | endosome |
| Cellular Component | GO:0098978 | glutamatergic synapse |
| Cellular Component | GO:0005764 | lysosome |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0098843 | postsynaptic endocytic zone |
| Cellular Component | GO:0098835 | presynaptic endocytic zone membrane |
| Cellular Component | GO:0005819 | spindle |
| Cellular Component | GO:0030672 | synaptic vesicle membrane |
| Molecular Function | GO:0032050 | clathrin heavy chain binding |
| Molecular Function | GO:0051020 | GTPase binding |
| Molecular Function | GO:0042277 | peptide binding |
| Molecular Function | GO:0044877 | protein-containing complex binding |
| Molecular Function | GO:0005198 | structural molecule activity |
| Biological Process | GO:0051301 | cell division |
| Biological Process | GO:0048268 | clathrin coat assembly |
| Biological Process | GO:0072583 | clathrin-dependent endocytosis |
| Biological Process | GO:0006897 | endocytosis |
| Biological Process | GO:0006886 | intracellular protein transport |
| Biological Process | GO:0048488 | synaptic vesicle endocytosis |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.