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Overview

Uniprot IDP08132
Protein NameAnnexin A4
Gene NameANXA4
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
218 EYKRISQKDIEQSIK
246 IVKCMRNKSAYFAER
57 QEIRTAYKSTIGRDL

Function

Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis

Protein Sequence

10 MAAKGGTVKA 20 ASGFNAAEDA 30 QTLRKAMKGL 40 GTDEDAIISV 50 LAYRSTAQRQ 60 EIRTAYKSTI 70 GRDLLDDLKS 80 ELSGNFEQVI 90 LGMMTPTVLY 100 DVQELRRAMK 110 GAGTDEGCLI 120 EILASRTPEE 130 IRRINQTYQL 140 QYGRSLEDDI 150 RSDTSFMFQR 160 VLVSLSAGGR 170 DEGNYLDDAL 180 VRQDAQDLYE 190 AGEKKWGTDE 200 VKFLTVLCSR 210 NRNHLLHVFD 220 EYKRISQKDI 230 EQSIKSETSG 240 SFEDALLAIV 250 KCMRNKSAYF 260 AERLYKSMKG 270 LGTDDNTLIR 280 VMVSRAEIDM 290 MDIRANFKRL 300 YGKSLYSFIK 310 GDTSGDYRKV LLILCGGDD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005886 plasma membrane
Cellular Component GO:0012506 vesicle membrane
Cellular Component GO:0042589 zymogen granule membrane
Molecular Function GO:0005509 calcium ion binding
Molecular Function GO:0005544 calcium-dependent phospholipid binding
Molecular Function GO:0001786 phosphatidylserine binding

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.