Overview
| Uniprot ID | P08170 |
| Protein Name | Seed linoleate 13S-lipoxygenase-1 |
| Gene Name | LOX1.1 |
| Organism | Glycine max |
Kla Sites from experimental identification
| Position |
Flanking peptide |
| 250 |
DENLGHLKSKDALEI |
| 252 |
NLGHLKSKDALEIGT |
| 427 |
INQLNSAKTYATRTI |
| 593 |
IKRGVAIKDPSTPHG |
| 655 |
WWKEAVEKGHGDLKD |
| 718 |
SRRLLPEKGTPEYEE |
| 777 |
PHWTSDSKALQAFQK |
| 784 |
KALQAFQKFGNKLKE |
Function
Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. With linoleate as substrate, L-1 shows a preference for carbon 13 as the site for hydroperoxidation (in contrast to L-2 and L-3, which utilize either carbon 9 or 13). At pH above 8.5, only (9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate is produced, but as the pH decreases, the proportion of (9S)-hydroperoxide increases linearly until at pH 6.0 it represents about 25 % of the products
Protein Sequence
10
MFSAGHKIKG
20
TVVLMPKNEL
30
EVNPDGSAVD
40
NLNAFLGRSV
50
SLQLISATKA
60
DAHGKGKVGK
70
DTFLEGINTS
80
LPTLGAGESA
90
FNIHFEWDGS
100
MGIPGAFYIK
110
NYMQVEFFLK
120
SLTLEAISNQ
130
GTIRFVCNSW
140
VYNTKLYKSV
150
RIFFANHTYV
160
PSETPAPLVS
170
YREEELKSLR
180
GNGTGERKEY
190
DRIYDYDVYN
200
DLGNPDKSEK
210
LARPVLGGSS
220
TFPYPRRGRT
230
GRGPTVTDPN
240
TEKQGEVFYV
250
PRDENLGHLK
260
SKDALEIGTK
270
SLSQIVQPAF
280
ESAFDLKSTP
290
IEFHSFQDVH
300
DLYEGGIKLP
310
RDVISTIIPL
320
PVIKELYRTD
330
GQHILKFPQP
340
HVVQVSQSAW
350
MTDEEFAREM
360
IAGVNPCVIR
370
GLEEFPPKSN
380
LDPAIYGDQS
390
SKITADSLDL
400
DGYTMDEALG
410
SRRLFMLDYH
420
DIFMPYVRQI
430
NQLNSAKTYA
440
TRTILFLRED
450
GTLKPVAIEL
460
SLPHSAGDLS
470
AAVSQVVLPA
480
KEGVESTIWL
490
LAKAYVIVND
500
SCYHQLMSHW
510
LNTHAAMEPF
520
VIATHRHLSV
530
LHPIYKLLTP
540
HYRNNMNINA
550
LARQSLINAN
560
GIIETTFLPS
570
KYSVEMSSAV
580
YKNWVFTDQA
590
LPADLIKRGV
600
AIKDPSTPHG
610
VRLLIEDYPY
620
AADGLEIWAA
630
IKTWVQEYVP
640
LYYARDDDVK
650
NDSELQHWWK
660
EAVEKGHGDL
670
KDKPWWPKLQ
680
TLEDLVEVCL
690
IIIWIASALH
700
AAVNFGQYPY
710
GGLIMNRPTA
720
SRRLLPEKGT
730
PEYEEMINNH
740
EKAYLRTITS
750
KLPTLISLSV
760
IEILSTHASD
770
EVYLGQRDNP
780
HWTSDSKALQ
790
AFQKFGNKLK
800
EIEEKLVRRN
810
NDPSLQGNRL
820
GPVQLPYTLL
830
YPSSEEGLTF
RGIPNSISI
Gene Ontology
| Classification |
GO ID |
Description |
| Cellular Component |
GO:0005737 |
cytoplasm |
| Molecular Function |
GO:0005506 |
iron ion binding |
| Molecular Function |
GO:0016165 |
linoleate 13S-lipoxygenase activity |
| Molecular Function |
GO:0102299 |
linolenate 9R-lipoxygenase activity |
| Molecular Function |
GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
| Biological Process |
GO:0006633 |
fatty acid biosynthetic process |
| Biological Process |
GO:0019395 |
fatty acid oxidation |
| Biological Process |
GO:0034440 |
lipid oxidation |
| Biological Process |
GO:0031408 |
oxylipin biosynthetic process |
Reference
[1] Xu C, Li J, Dong C, Zhang Y, Li H et al.. Lactylome Profiling Reveals the Potential Role of Lysine Lactylation in Regulating Soybean Seed Quality.. J Agric Food Chem 73(23):14666-14676. 2025 Jun 11. PMID: 40440508.