Search Results
Overview
| Uniprot ID | P08243 |
|---|---|
| Protein Name | Asparagine synthetase [glutamine-hydrolyzing] |
| Gene Name | ASNS |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 245 | LFNNAVKKRLMTDRR |
| 478 | SDGITSVKNSWFKIL |
| 556 | ARTLTHYKSAVKA** |
Function
No function data available.
Protein Sequence
10
MCGIWALFGS
20
DDCLSVQCLS
30
AMKIAHRGPD
40
AFRFENVNGY
50
TNCCFGFHRL
60
AVVDPLFGMQ
70
PIRVKKYPYL
80
WLCYNGEIYN
90
HKKMQQHFEF
100
EYQTKVDGEI
110
ILHLYDKGGI
120
EQTICMLDGV
130
FAFVLLDTAN
140
KKVFLGRDTY
150
GVRPLFKAMT
160
EDGFLAVCSE
170
AKGLVTLKHS
180
ATPFLKVEPF
190
LPGHYEVLDL
200
KPNGKVASVE
210
MVKYHHCRDV
220
PLHALYDNVE
230
KLFPGFEIET
240
VKNNLRILFN
250
NAVKKRLMTD
260
RRIGCLLSGG
270
LDSSLVAATL
280
LKQLKEAQVQ
290
YPLQTFAIGM
300
EDSPDLLAAR
310
KVADHIGSEH
320
YEVLFNSEEG
330
IQALDEVIFS
340
LETYDITTVR
350
ASVGMYLISK
360
YIRKNTDSVV
370
IFSGEGSDEL
380
TQGYIYFHKA
390
PSPEKAEEES
400
ERLLRELYLF
410
DVLRADRTTA
420
AHGLELRVPF
430
LDHRFSSYYL
440
SLPPEMRIPK
450
NGIEKHLLRE
460
TFEDSNLIPK
470
EILWRPKEAF
480
SDGITSVKNS
490
WFKILQEYVE
500
HQVDDAMMAN
510
AAQKFPFNTP
520
KTKEGYYYRQ
530
VFERHYPGRA
540
DWLSHYWMPK
550
WINATDPSAR
560
TLTHYKSAVK
A
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Molecular Function | GO:0004066 | asparagine synthase (glutamine-hydrolyzing) activity |
| Molecular Function | GO:0005524 | ATP binding |
| Biological Process | GO:0042149 | cellular response to glucose starvation |
| Biological Process | GO:0070981 | L-asparagine biosynthetic process |
| Biological Process | GO:0043066 | negative regulation of apoptotic process |
| Biological Process | GO:0045931 | positive regulation of mitotic cell cycle |
Reference
[1] Cheng Z, Huang H, Li M, Chen Y. Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.. iScience 27(1):108645. 2024 Jan 19. PMID: 38155775.
[2] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.