Search Results
Overview
| Uniprot ID | P08590 |
|---|---|
| Protein Name | Myosin light chain 3 |
| Gene Name | MYL3 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 14 | EPKKDDAKAAPKAAP |
| 18 | DDAKAAPKAAPAPAP |
Function
Regulatory light chain of myosin. Does not bind calcium
Protein Sequence
10
MAPKKPEPKK
20
DDAKAAPKAA
30
PAPAPPPEPE
40
RPKEVEFDAS
50
KIKIEFTPEQ
60
IEEFKEAFML
70
FDRTPKCEMK
80
ITYGQCGDVL
90
RALGQNPTQA
100
EVLRVLGKPR
110
QEELNTKMMD
120
FETFLPMLQH
130
ISKNKDTGTY
140
EDFVEGLRVF
150
DKEGNGTVMG
160
AELRHVLATL
170
GERLTEDEVE
180
KLMAGQEDSN
190
GCINYEAFVK
HIMSS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0031672 | A band |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0031674 | I band |
| Cellular Component | GO:0005859 | muscle myosin complex |
| Cellular Component | GO:0016460 | myosin II complex |
| Cellular Component | GO:0030017 | sarcomere |
| Molecular Function | GO:0003785 | actin monomer binding |
| Molecular Function | GO:0005509 | calcium ion binding |
| Molecular Function | GO:0003774 | cytoskeletal motor activity |
| Molecular Function | GO:0032038 | myosin II heavy chain binding |
| Molecular Function | GO:0008307 | structural constituent of muscle |
| Biological Process | GO:0060048 | cardiac muscle contraction |
| Biological Process | GO:0006936 | muscle contraction |
| Biological Process | GO:0006942 | regulation of striated muscle contraction |
| Biological Process | GO:0002026 | regulation of the force of heart contraction |
| Biological Process | GO:0007519 | skeletal muscle tissue development |
| Biological Process | GO:0055010 | ventricular cardiac muscle tissue morphogenesis |
Reference
[1] Lin Y, Chen M, Wang D, Yu Y, Chen R et al.. Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.. J Proteome Res 22(6):1712-1722. 2023 Jun 2. PMID: 37159428.