Search Results
Overview
| Uniprot ID | P09117 |
|---|---|
| Protein Name | Fructose-bisphosphate aldolase C |
| Gene Name | Aldoc |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 101 | FVRTIQEKGILVGIK |
| 108 | KGILVGIKVDKGVVP |
| 13 | PALSAEQKKELSDIA |
| 14 | ALSAEQKKELSDIAL |
| 153 | AKWRCVLKISDRTPS |
| 230 | YLEGTLLKPNMVTPG |
| 28 | LRIVAPGKGILAADE |
| 330 | AATEEFIKRAEMNGL |
| 42 | ESVGSMAKRLSQIGV |
Function
Catalyzes the reversible conversion of beta-D-fructose 1,6-bisphosphate (FBP) into two triose phosphate and plays a key role in glycolysis and gluconeogenesis
Protein Sequence
10
MPHSYPALSA
20
EQKKELSDIA
30
LRIVAPGKGI
40
LAADESVGSM
50
AKRLSQIGVE
60
NTEENRRLYR
70
QVLFSADDRV
80
KKCIGGVIFF
90
HETLYQKDDN
100
GVPFVRTIQE
110
KGILVGIKVD
120
KGVVPLAGTD
130
GETTTQGLDG
140
LLERCAQYKK
150
DGADFAKWRC
160
VLKISDRTPS
170
ALAILENANV
180
LARYASICQQ
190
NGIVPIVEPE
200
ILPDGDHDLK
210
RCQFVTEKVL
220
AAVYKALSDH
230
HVYLEGTLLK
240
PNMVTPGHAC
250
PIKYSPEEIA
260
MATVTALRRT
270
VPPAVPGVTF
280
LSGGQSEEEA
290
SLNLNAINRC
300
SLPRPWALTF
310
SYGRALQASA
320
LSAWRGQRDN
330
AGAATEEFIK
340
RAEMNGLAAQ
350
GKYEGSGDGG
360
AAAQSLYVAN
HAY
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030424 | axon |
| Molecular Function | GO:0044877 | protein-containing complex binding |
| Biological Process | GO:0031100 | animal organ regeneration |
| Biological Process | GO:0030855 | epithelial cell differentiation |
| Biological Process | GO:0030388 | fructose 1,6-bisphosphate metabolic process |
| Biological Process | GO:0006094 | gluconeogenesis |
| Biological Process | GO:0006096 | glycolytic process |
| Biological Process | GO:0001666 | response to hypoxia |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0099524 | postsynaptic cytosol |
| Molecular Function | GO:0008092 | cytoskeletal protein binding |
| Molecular Function | GO:0004332 | fructose-bisphosphate aldolase activity |
| Molecular Function | GO:0042802 | identical protein binding |
Reference
[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.