Search Results
Overview
| Uniprot ID | P09455 |
|---|---|
| Protein Name | Retinol-binding protein 1 |
| Gene Name | RBP1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 128 | RVEGVVCKQVFKKVQ |
| 32 | DVNVALRKIANLLKP |
Function
Cytoplasmic retinol-binding protein (PubMed:22665496, PubMed:26900151, PubMed:28057518). Accepts retinol from the transport protein STRA6, and thereby contributes to retinol uptake, storage and retinoid homeostasis (PubMed:15632377, PubMed:22665496)
Protein Sequence
10
MPVDFTGYWK
20
MLVNENFEEY
30
LRALDVNVAL
40
RKIANLLKPD
50
KEIVQDGDHM
60
IIRTLSTFRN
70
YIMDFQVGKE
80
FEEDLTGIDD
90
RKCMTTVSWD
100
GDKLQCVQKG
110
EKEGRGWTQW
120
IEGDELHLEM
130
RVEGVVCKQV
FKKVQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005811 | lipid droplet |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:1904768 | all-trans-retinol binding |
| Molecular Function | GO:0005504 | fatty acid binding |
| Molecular Function | GO:0140104 | molecular carrier activity |
| Molecular Function | GO:0016918 | retinal binding |
| Molecular Function | GO:0005501 | retinoid binding |
| Biological Process | GO:0015908 | fatty acid transport |
| Biological Process | GO:0055088 | lipid homeostasis |
| Biological Process | GO:0002138 | retinoic acid biosynthetic process |
| Biological Process | GO:0001523 | retinoid metabolic process |
| Biological Process | GO:0006776 | vitamin A metabolic process |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] Yang YH, Wang QC, Kong J, Yang JT, Liu JF. Global profiling of lysine lactylation in human lungs.. Proteomics 23(15):e2200437. 2023 Aug. PMID: 37170646.