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Overview

Uniprot IDP09541
Protein NameMyosin light chain 4
Gene NameMyl4
OrganismMus musculus

Kla Sites from experimental identification

Position Flanking peptide
38 KDSAFDPKSVKIDFS

Function

Regulatory light chain of myosin. Does not bind calcium

Protein Sequence

10 MPPKKPEPKK 20 EAAKPAAAPA 30 PAASAAPEPL 40 KDSAFDPKSV 50 KIDFSADQIE 60 EFKEAFSLFD 70 RTPTGEMKIT 80 YGQCGDVLRA 90 LGQNPTNAEV 100 LRVLGKPKPE 110 EMSSKTLDFE 120 MFLPILQHIS 130 RNKEQGTYED 140 FVEGLRVFDK 150 ESNGTVMGAE 160 LRHVLATLGE 170 KMSEAEVEQL 180 LSGQEDANGC 190 INYEAFVKHI MSG

Gene Ontology

Classification GO ID Description
Cellular Component GO:0031672 A band
Cellular Component GO:0016460 myosin II complex
Cellular Component GO:0016461 unconventional myosin complex
Molecular Function GO:0051015 actin filament binding
Molecular Function GO:0003785 actin monomer binding
Molecular Function GO:0005509 calcium ion binding
Molecular Function GO:0003774 cytoskeletal motor activity
Biological Process GO:0060048 cardiac muscle contraction
Biological Process GO:0006936 muscle contraction
Biological Process GO:0030049 muscle filament sliding
Biological Process GO:0002026 regulation of the force of heart contraction

Reference

[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.