Search Results
Overview
| Uniprot ID | P0CAP1 |
|---|---|
| Protein Name | Myocardial zonula adherens protein |
| Gene Name | MYZAP |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 113 | DVRATLEKVRKRMYG |
Function
Plays a role in cellular signaling via Rho-related GTP-binding proteins and subsequent activation of transcription factor SRF (By similarity). Targets TJP1 to cell junctions. In cortical neurons, may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1 (By similarity)
Protein Sequence
10
MLRSTSTVTL
20
LSGGAARTPG
30
APSRRANVCR
40
LRLTVPPESP
50
VPEQCEKKIE
60
RKEQLLDLSN
70
GEPTRKLPQG
80
VVYGVVRRSD
90
QNQQKEMVVY
100
GWSTSQLKEE
110
MNYIKDVRAT
120
LEKVRKRMYG
130
DYDEMRQKIR
140
QLTQELSVSH
150
AQQEYLENHI
160
QTQSSALDRF
170
NAMNSALASD
180
SIGLQKTLVD
190
VTLENSNIKD
200
QIRNLQQTYE
210
ASMDKLREKQ
220
RQLEVAQVEN
230
QLLKMKVESS
240
QEANAEVMRE
250
MTKKLYSQYE
260
EKLQEEQRKH
270
SAEKEALLEE
280
TNSFLKAIEE
290
ANKKMQAAEI
300
SLEEKDQRIG
310
ELDRLIERME
320
KERHQLQLQL
330
LEHETEMSGE
340
LTDSDKERYQ
350
QLEEASASLR
360
ERIRHLDDMV
370
HCQQKKVKQM
380
VEEIESLKKK
390
LQQKQLLILQ
400
LLEKISFLEG
410
ENNELQSRLD
420
YLTETQAKTE
430
VETREIGVGC
440
DLLPSQTGRT
450
REIVMPSRNY
460
TPYTRVLELT
MKKTLT
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0070161 | anchoring junction |
| Cellular Component | GO:0030864 | cortical actin cytoskeleton |
| Cellular Component | GO:0009898 | cytoplasmic side of plasma membrane |
| Cellular Component | GO:0031674 | I band |
| Cellular Component | GO:0005665 | RNA polymerase II, core complex |
| Cellular Component | GO:0030018 | Z disc |
| Biological Process | GO:0035556 | intracellular signal transduction |
Reference
[1] Yang YH, Wang QC, Kong J, Yang JT, Liu JF. Global profiling of lysine lactylation in human lungs.. Proteomics 23(15):e2200437. 2023 Aug. PMID: 37170646.