Search Results
Overview
| Uniprot ID | P0CG30 |
|---|---|
| Protein Name | Glutathione S-transferase theta-2B |
| Gene Name | GSTT2B |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 37 | LRTVDLVKGQHKSKE |
| 41 | DLVKGQHKSKEFLQI |
| 43 | VKGQHKSKEFLQINS |
Function
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (PubMed:1417752). Has a sulfatase activity (PubMed:1417752)
Protein Sequence
10
MGLELFLDLV
20
SQPSRAVYIF
30
AKKNGIPLEL
40
RTVDLVKGQH
50
KSKEFLQINS
60
LGKLPTLKDG
70
DFILTESSAI
80
LIYLSCKYQT
90
PDHWYPSDLQ
100
ARARVHEYLG
110
WHADCIRGTF
120
GIPLWVQVLG
130
PLIGVQVPEE
140
KVERNRTAMD
150
QALQWLEDKF
160
LGDRPFLAGQ
170
QVTLADLMAL
180
EELMQPVALG
190
YELFEGRPRL
200
AAWRGRVEAF
210
LGAELCQEAH
220
SIILSILEQA
230
AKKTLPTPSP
240
EAYQAMLLRI
ARIP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0070062 | extracellular exosome |
| Molecular Function | GO:0004364 | glutathione transferase activity |
| Biological Process | GO:0006749 | glutathione metabolic process |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.