Search Results

Overview

Uniprot IDP0DJI8
Protein NameSerum amyloid A-1 protein
Gene NameSAA1
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
52 ANYIGSDKYFHARGN

Function

Major acute phase protein

Protein Sequence

10 MKLLTGLVFC 20 SLVLGVSSRS 30 FFSFLGEAFD 40 GARDMWRAYS 50 DMREANYIGS 60 DKYFHARGNY 70 DAAKRGPGGA 80 WAAEVITDAR 90 ENIQRFFGHG 100 AEDSLADQAA 110 NEWGRSGKDP 120 NHFRPAGLPE KY

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005881 cytoplasmic microtubule
Cellular Component GO:0071682 endocytic vesicle lumen
Cellular Component GO:0070062 extracellular exosome
Cellular Component GO:0005576 extracellular region
Cellular Component GO:0034364 high-density lipoprotein particle
Molecular Function GO:0001664 G protein-coupled receptor binding
Molecular Function GO:0008201 heparin binding
Biological Process GO:0006953 acute-phase response
Biological Process GO:0048247 lymphocyte chemotaxis
Biological Process GO:0048246 macrophage chemotaxis
Biological Process GO:0050728 negative regulation of inflammatory response
Biological Process GO:0030593 neutrophil chemotaxis
Biological Process GO:0030168 platelet activation
Biological Process GO:0045785 positive regulation of cell adhesion
Biological Process GO:0001819 positive regulation of cytokine production
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0032732 positive regulation of interleukin-1 production
Biological Process GO:0050708 regulation of protein secretion

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.