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Overview

Uniprot IDP10244
Protein NameMyb-related protein B
Gene NameMYBL2
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
411 GTPPSVLKRQRKRRV

Function

Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene

Protein Sequence

10 MSRRTRCEDL 20 DELHYQDTDS 30 DVPEQRDSKC 40 KVKWTHEEDE 50 QLRALVRQFG 60 QQDWKFLASH 70 FPNRTDQQCQ 80 YRWLRVLNPD 90 LVKGPWTKEE 100 DQKVIELVKK 110 YGTKQWTLIA 120 KHLKGRLGKQ 130 CRERWHNHLN 140 PEVKKSCWTE 150 EEDRIICEAH 160 KVLGNRWAEI 170 AKMLPGRTDN 180 AVKNHWNSTI 190 KRKVDTGGFL 200 SESKDCKPPV 210 YLLLELEDKD 220 GLQSAQPTEG 230 QGSLLTNWPS 240 VPPTIKEEEN 250 SEEELAAATT 260 SKEQEPIGTD 270 LDAVRTPEPL 280 EEFPKREDQE 290 GSPPETSLPY 300 KWVVEAANLL 310 IPAVGSSLSE 320 ALDLIESDPD 330 AWCDLSKFDL 340 PEEPSAEDSI 350 NNSLVQLQAS 360 HQQQVLPPRQ 370 PSALVPSVTE 380 YRLDGHTISD 390 LSRSSRGELI 400 PISPSTEVGG 410 SGIGTPPSVL 420 KRQRKRRVAL 430 SPVTENSTSL 440 SFLDSCNSLT 450 PKSTPVKTLP 460 FSPSQFLNFW 470 NKQDTLELES 480 PSLTSTPVCS 490 QKVVVTTPLH 500 RDKTPLHQKH 510 AAFVTPDQKY 520 SMDNTPHTPT 530 PFKNALEKYG 540 PLKPLPQTPH 550 LEEDLKEVLR 560 SEAGIELIIE 570 DDIRPEKQKR 580 KPGLRRSPIK 590 KVRKSLALDI 600 VDEDVKLMMS 610 TLPKSLSLPT 620 TAPSNSSSLT 630 LSGIKEDNSL 640 LNQGFLQAKP 650 EKAAVAQKPR 660 SHFTTPAPMS 670 SAWKTVACGG 680 TRDQLFMQEK 690 ARQLLGRLKP 700 SHTSRTLILS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0031523 Myb complex
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Molecular Function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
Molecular Function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
Molecular Function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
Molecular Function GO:1990837 sequence-specific double-stranded DNA binding
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0000278 mitotic cell cycle
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II

Reference

PMID: N/A