Search Results
Overview
| Uniprot ID | P10649 |
|---|---|
| Protein Name | Glutathione S-transferase Mu 1 |
| Gene Name | Gstm1 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 144 | LYSEFLGKRPWFAGD |
Function
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers
Protein Sequence
10
MPMILGYWNV
20
RGLTHPIRML
30
LEYTDSSYDE
40
KRYTMGDAPD
50
FDRSQWLNEK
60
FKLGLDFPNL
70
PYLIDGSHKI
80
TQSNAILRYL
90
ARKHHLDGET
100
EEERIRADIV
110
ENQVMDTRMQ
120
LIMLCYNPDF
130
EKQKPEFLKT
140
IPEKMKLYSE
150
FLGKRPWFAG
160
DKVTYVDFLA
170
YDILDQYRMF
180
EPKCLDAFPN
190
LRDFLARFEG
200
LKKISAYMKS
210
SRYIATPIFS
KMAHWSNK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0043209 | myelin sheath |
| Cellular Component | GO:0032991 | protein-containing complex |
| Molecular Function | GO:0019899 | enzyme binding |
| Molecular Function | GO:0043295 | glutathione binding |
| Molecular Function | GO:0004364 | glutathione transferase activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0016151 | nickel cation binding |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Molecular Function | GO:0019901 | protein kinase binding |
| Molecular Function | GO:0005496 | steroid binding |
| Biological Process | GO:0071466 | cellular response to xenobiotic stimulus |
| Biological Process | GO:1901687 | glutathione derivative biosynthetic process |
| Biological Process | GO:0006749 | glutathione metabolic process |
| Biological Process | GO:0051122 | hepoxilin biosynthetic process |
| Biological Process | GO:0006693 | prostaglandin metabolic process |
| Biological Process | GO:0042178 | xenobiotic catabolic process |
Reference
[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.