Search Results
Overview
| Uniprot ID | P10915 |
|---|---|
| Protein Name | Hyaluronan and proteoglycan link protein 1 |
| Gene Name | HAPLN1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 76 | AFGSGIHKIRIKWTK |
Function
Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix
Protein Sequence
10
MKSLLLLVLI
20
SICWADHLSD
30
NYTLDHDRAI
40
HIQAENGPHL
50
LVEAEQAKVF
60
SHRGGNVTLP
70
CKFYRDPTAF
80
GSGIHKIRIK
90
WTKLTSDYLK
100
EVDVFVSMGY
110
HKKTYGGYQG
120
RVFLKGGSDS
130
DASLVITDLT
140
LEDYGRYKCE
150
VIEGLEDDTV
160
VVALDLQGVV
170
FPYFPRLGRY
180
NLNFHEAQQA
190
CLDQDAVIAS
200
FDQLYDAWRG
210
GLDWCNAGWL
220
SDGSVQYPIT
230
KPREPCGGQN
240
TVPGVRNYGF
250
WDKDKSRYDV
260
FCFTSNFNGR
270
FYYLIHPTKL
280
TYDEAVQACL
290
NDGAQIAKVG
300
QIFAAWKILG
310
YDRCDAGWLA
320
DGSVRYPISR
330
PRRRCSPTEA
340
AVRFVGFPDK
350
KHKLYGVYCF
RAYN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0031012 | extracellular matrix |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0140150 | gel phase of interstitial matrix |
| Cellular Component | GO:0072534 | perineuronal net |
| Cellular Component | GO:0045202 | synapse |
| Molecular Function | GO:0005540 | hyaluronic acid binding |
| Biological Process | GO:0007155 | cell adhesion |
| Biological Process | GO:0007417 | central nervous system development |
| Biological Process | GO:0001501 | skeletal system development |
Reference
[1] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.