Search Results
Overview
| Uniprot ID | P11348 |
|---|---|
| Protein Name | Dihydropteridine reductase |
| Gene Name | Qdpr |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 124 | HLATKHLKEGGLLTL |
Function
Catalyzes the conversion of quinonoid dihydrobiopterin into tetrahydrobiopterin
Protein Sequence
10
MAASGEARRV
20
LVYGGRGALG
30
SRCVQAFRAR
40
NWWVASIDVV
50
ENEEASASVI
60
VKMTDSFTEQ
70
ADQVTAEVGK
80
LLGDQKVDAI
90
LCVAGGWAGG
100
NAKSKSLFKN
110
CDLMWKQSIW
120
TSTISSHLAT
130
KHLKEGGLLT
140
LAGAKAALDG
150
TPGMIGYGMA
160
KGAVHQLCQS
170
LAGKNSGMPS
180
GAAAIAVLPV
190
TLDTPMNRKS
200
MPEADFSSWT
210
PLEFLVETFH
220
DWITGNKRPN
230
SGSLIQVVTT
240
DGKTELTPAY
F
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0004155 | 6,7-dihydropteridine reductase activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0070404 | NADH binding |
| Molecular Function | GO:0070402 | NADPH binding |
| Biological Process | GO:0071466 | cellular response to xenobiotic stimulus |
| Biological Process | GO:0006559 | L-phenylalanine catabolic process |
| Biological Process | GO:0001889 | liver development |
| Biological Process | GO:0010044 | response to aluminum ion |
| Biological Process | GO:0033762 | response to glucagon |
| Biological Process | GO:0010288 | response to lead ion |
| Biological Process | GO:0006729 | tetrahydrobiopterin biosynthetic process |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.