Search Results
Overview
| Uniprot ID | P11404 |
|---|---|
| Protein Name | Fatty acid-binding protein, heart |
| Gene Name | Fabp3 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 10 | DAFVGTWKLVDSKNF |
| 15 | TWKLVDSKNFDDYMK |
| 22 | KNFDDYMKSLGVGFA |
| 38 | RQVASMTKPTTIIEK |
| 82 | TADDRKVKSLVTLDG |
| 91 | LVTLDGGKLIHVQKW |
Function
FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters
Protein Sequence
10
MADAFVGTWK
20
LVDSKNFDDY
30
MKSLGVGFAT
40
RQVASMTKPT
50
TIIEKNGDTI
60
TIKTQSTFKN
70
TEINFQLGIE
80
FDEVTADDRK
90
VKSLVTLDGG
100
KLIHVQKWNG
110
QETTLTRELV
120
DGKLILTLTH
130
GSVVSTRTYE
KEA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0016528 | sarcoplasm |
| Molecular Function | GO:0008092 | cytoskeletal protein binding |
| Molecular Function | GO:0005504 | fatty acid binding |
| Molecular Function | GO:0050543 | icosatetraenoic acid binding |
| Molecular Function | GO:0036041 | long-chain fatty acid binding |
| Molecular Function | GO:0005324 | long-chain fatty acid transmembrane transporter activity |
| Molecular Function | GO:0070538 | oleic acid binding |
| Biological Process | GO:0050873 | brown fat cell differentiation |
| Biological Process | GO:0042632 | cholesterol homeostasis |
| Biological Process | GO:0006631 | fatty acid metabolic process |
| Biological Process | GO:0032365 | intracellular lipid transport |
| Biological Process | GO:0015909 | long-chain fatty acid transport |
| Biological Process | GO:0055091 | phospholipid homeostasis |
| Biological Process | GO:0140214 | positive regulation of long-chain fatty acid import into cell |
| Biological Process | GO:0071073 | positive regulation of phospholipid biosynthetic process |
| Biological Process | GO:0046320 | regulation of fatty acid oxidation |
| Biological Process | GO:2001245 | regulation of phosphatidylcholine biosynthetic process |
| Biological Process | GO:0070542 | response to fatty acid |
| Biological Process | GO:0032868 | response to insulin |
| Biological Process | GO:0009410 | response to xenobiotic stimulus |
Reference
[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.
[2] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.