Search Results
Overview
| Uniprot ID | P12026 |
|---|---|
| Protein Name | Acyl-CoA-binding protein |
| Gene Name | DBI |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 14 | EKAAEEVKNLKTKPA |
| 55 | LDLKGKAKWDAWNGL |
| 77 | AMKAYINKVEELKKK |
Function
Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor
Protein Sequence
10
MSQAEFEKAA
20
EEVKNLKTKP
30
ADDEMLFIYS
40
HYKQATVGDI
50
NTERPGILDL
60
KGKAKWDAWN
70
GLKGTSKEDA
80
MKAYINKVEE
LKKKYGI
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Molecular Function | GO:0000062 | fatty-acyl-CoA binding |
| Biological Process | GO:0042742 | defense response to bacterium |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.