Search Results
Overview
| Uniprot ID | P12829 |
|---|---|
| Protein Name | Myosin light chain 4 |
| Gene Name | MYL4 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 144 | EGLRVFDKESNGTVM |
Function
Regulatory light chain of myosin. Does not bind calcium
Protein Sequence
10
MAPKKPEPKK
20
EAAKPAPAPA
30
PAPAPAPAPA
40
PEAPKEPAFD
50
PKSVKIDFTA
60
DQIEEFKEAF
70
SLFDRTPTGE
80
MKITYGQCGD
90
VLRALGQNPT
100
NAEVLRVLGK
110
PKPEEMNVKM
120
LDFETFLPIL
130
QHISRNKEQG
140
TYEDFVEGLR
150
VFDKESNGTV
160
MGAELRHVLA
170
TLGEKMTEAE
180
VEQLLAGQED
190
ANGCINYEAF
VKHIMSG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016460 | myosin II complex |
| Cellular Component | GO:0031672 | A band |
| Cellular Component | GO:0005829 | cytosol |
| Molecular Function | GO:0051015 | actin filament binding |
| Molecular Function | GO:0003785 | actin monomer binding |
| Molecular Function | GO:0005509 | calcium ion binding |
| Molecular Function | GO:0032038 | myosin II heavy chain binding |
| Biological Process | GO:0060048 | cardiac muscle contraction |
| Biological Process | GO:0006936 | muscle contraction |
| Biological Process | GO:0002026 | regulation of the force of heart contraction |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.