Search Results
Overview
| Uniprot ID | P12970 |
|---|---|
| Protein Name | Large ribosomal subunit protein eL8 |
| Gene Name | Rpl7a |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 11 | GKKAKGKKVAPAPAV |
| 125 | AEKKAAGKGDVPTKR |
| 20 | APAPAVVKKQEAKKV |
Function
Component of the large ribosomal subunit (PubMed:36517592). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592)
Protein Sequence
10
MPKGKKAKGK
20
KVAPAPAVVK
30
KQEAKKVVNP
40
LFEKRPKNFG
50
IGQDIQPKRD
60
LTRFVKWPRY
70
IRLQRQRAIL
80
YKRLKVPPAI
90
NQFTQALDRQ
100
TATQLLKLAH
110
KYRPETKQEK
120
KQRLLARAEK
130
KAAGKGDVPT
140
KRPPVLRAGV
150
NTVTTLVENK
160
KAQLVVIAHD
170
VDPIELVVFL
180
PALCRKMGVP
190
YCIIKGKARL
200
GHLVHRKTCT
210
TVAFTQVNSE
220
DKGALAKLVE
230
AIRTNYNDRY
240
DEIRRHWGGN
250
VLGPKSVARI
260
AKLEKAKAKE
LATKLG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0022625 | cytosolic large ribosomal subunit |
| Cellular Component | GO:0022626 | cytosolic ribosome |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0098794 | postsynapse |
| Cellular Component | GO:0098793 | presynapse |
| Cellular Component | GO:0005840 | ribosome |
| Cellular Component | GO:0045202 | synapse |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0003735 | structural constituent of ribosome |
| Biological Process | GO:0002181 | cytoplasmic translation |
| Biological Process | GO:0000470 | maturation of LSU-rRNA |
| Biological Process | GO:1901740 | negative regulation of myoblast fusion |
| Biological Process | GO:0007283 | spermatogenesis |
| Biological Process | GO:0006941 | striated muscle contraction |
| Biological Process | GO:0140242 | translation at postsynapse |
| Biological Process | GO:0140236 | translation at presynapse |
Reference
[1] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.