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Overview

Uniprot IDP13591
Protein NameNeural cell adhesion molecule 1
Gene NameNCAM1
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
634 SIKVNLIKQDDGGSP
781 EGKAAFSKDESKEPI
835 ECQETETKPAPAEVK

Function

This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc

Protein Sequence

10 MLQTKDLIWT 20 LFFLGTAVSL 30 QVDIVPSQGE 40 ISVGESKFFL 50 CQVAGDAKDK 60 DISWFSPNGE 70 KLTPNQQRIS 80 VVWNDDSSST 90 LTIYNANIDD 100 AGIYKCVVTG 110 EDGSESEATV 120 NVKIFQKLMF 130 KNAPTPQEFR 140 EGEDAVIVCD 150 VVSSLPPTII 160 WKHKGRDVIL 170 KKDVRFIVLS 180 NNYLQIRGIK 190 KTDEGTYRCE 200 GRILARGEIN 210 FKDIQVIVNV 220 PPTIQARQNI 230 VNATANLGQS 240 VTLVCDAEGF 250 PEPTMSWTKD 260 GEQIEQEEDD 270 EKYIFSDDSS 280 QLTIKKVDKN 290 DEAEYICIAE 300 NKAGEQDATI 310 HLKVFAKPKI 320 TYVENQTAME 330 LEEQVTLTCE 340 ASGDPIPSIT 350 WRTSTRNISS 360 EEKASWTRPE 370 KQETLDGHMV 380 VRSHARVSSL 390 TLKSIQYTDA 400 GEYICTASNT 410 IGQDSQSMYL 420 EVQYAPKLQG 430 PVAVYTWEGN 440 QVNITCEVFA 450 YPSATISWFR 460 DGQLLPSSNY 470 SNIKIYNTPS 480 ASYLEVTPDS 490 ENDFGNYNCT 500 AVNRIGQESL 510 EFILVQADTP 520 SSPSIDQVEP 530 YSSTAQVQFD 540 EPEATGGVPI 550 LKYKAEWRAV 560 GEEVWHSKWY 570 DAKEASMEGI 580 VTIVGLKPET 590 TYAVRLAALN 600 GKGLGEISAA 610 SEFKTQPVQG 620 EPSAPKLEGQ 630 MGEDGNSIKV 640 NLIKQDDGGS 650 PIRHYLVRYR 660 ALSSEWKPEI 670 RLPSGSDHVM 680 LKSLDWNAEY 690 EVYVVAENQQ 700 GKSKAAHFVF 710 RTSAQPTAIP 720 ANGSPTSGLS 730 TGAIVGILIV 740 IFVLLLVVVD 750 ITCYFLNKCG 760 LFMCIAVNLC 770 GKAGPGAKGK 780 DMEEGKAAFS 790 KDESKEPIVE 800 VRTEEERTPN 810 HDGGKHTEPN 820 ETTPLTEPEK 830 GPVEAKPECQ 840 ETETKPAPAE 850 VKTVPNDATQ TKENESKA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0000139 Golgi membrane
Cellular Component GO:0016020 membrane
Cellular Component GO:0043005 neuron projection
Cellular Component GO:0005886 plasma membrane
Molecular Function GO:0001618 virus receptor activity
Biological Process GO:0007155 cell adhesion
Biological Process GO:0071679 commissural neuron axon guidance
Biological Process GO:0001837 epithelial to mesenchymal transition
Biological Process GO:2001260 regulation of semaphorin-plexin signaling pathway
Cellular Component GO:0009986 cell surface
Cellular Component GO:0005829 cytosol
Cellular Component GO:0009897 external side of plasma membrane
Cellular Component GO:0031012 extracellular matrix
Cellular Component GO:0005576 extracellular region

Reference

[1] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.