Search Results
Overview
| Uniprot ID | P14057 |
|---|---|
| Protein Name | Nuclear factor 1 |
| Gene Name | NFI |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 79 | RLLAKLRKDIRPECR |
| 96 | FVLAITGKKAPGCVL |
| 97 | VLAITGKKAPGCVLS |
Function
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication
Protein Sequence
10
MGSRLTQDEF
20
HPFIEALLPH
30
VRAFAYTWFN
40
LQARKRKYFK
50
KHEKRMSKDE
60
ERAVKDELLG
70
EKAEVKQKWA
80
SRLLAKLRKD
90
IRPECREDFV
100
LAITGKKAPG
110
CVLSNPDQKG
120
KMRRIDCLRQ
130
ADKVWRLDLV
140
MVILFKGIPL
150
ESTDGERLVK
160
AAQCGHPVLC
170
VQPHHIGVAV
180
KELDLYLAYF
190
VRERGEAGRA
200
RGRGSDGREG
210
MRRASQSGRP
220
GESGPAGLRD
230
QAGTRSLGWA
G
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| Biological Process | GO:0006260 | DNA replication |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0045893 | positive regulation of DNA-templated transcription |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.