Search Results
Overview
| Uniprot ID | P14148 |
|---|---|
| Protein Name | Large ribosomal subunit protein uL30 |
| Gene Name | Rpl7 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 10 | AVPEKKKKVATVPGT |
| 19 | ATVPGTLKKKVPAGP |
| 32 | GPKTLKKKVPAVPET |
Function
Component of the large ribosomal subunit (PubMed:36517592). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592). Binds to G-rich structures in 28S rRNA and in mRNAs (By similarity). Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity)
Protein Sequence
10
MEAVPEKKKK
20
VATVPGTLKK
30
KVPAGPKTLK
40
KKVPAVPETL
50
KKKRRNFAEL
60
KVKRLRKKFA
70
LKTLRKARRK
80
LIYEKAKHYH
90
KEYRQMYRTE
100
IRMARMARKA
110
GNFYVPAEPK
120
LAFVIRIRGI
130
NGVSPKVRKV
140
LQLLRLRQIF
150
NGTFVKLNKA
160
SINMLRIVEP
170
YIAWGYPNLK
180
SVNELIYKRG
190
YGKINKKRIA
200
LTDNSLIARS
210
LGKFGIICME
220
DLIHEIYTVG
230
KRFKEANNFL
240
WPFKLSSPRG
250
GMKKKTTHFV
260
EGGDAGNRED
270
QINRLIRRMN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0031672 | A band |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0022625 | cytosolic large ribosomal subunit |
| Cellular Component | GO:0022626 | cytosolic ribosome |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0098794 | postsynapse |
| Cellular Component | GO:0014069 | postsynaptic density |
| Cellular Component | GO:0098793 | presynapse |
| Cellular Component | GO:1990904 | ribonucleoprotein complex |
| Cellular Component | GO:0005840 | ribosome |
| Cellular Component | GO:0045202 | synapse |
| Molecular Function | GO:0008097 | 5S rRNA binding |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0003729 | mRNA binding |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0003735 | structural constituent of ribosome |
| Biological Process | GO:0002181 | cytoplasmic translation |
| Biological Process | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| Biological Process | GO:1901740 | negative regulation of myoblast fusion |
| Biological Process | GO:0042273 | ribosomal large subunit biogenesis |
| Biological Process | GO:0006364 | rRNA processing |
| Biological Process | GO:0007283 | spermatogenesis |
| Biological Process | GO:0006941 | striated muscle contraction |
| Biological Process | GO:0006412 | translation |
| Biological Process | GO:0140242 | translation at postsynapse |
| Biological Process | GO:0140236 | translation at presynapse |
Reference
[1] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.