Search Results
Overview
| Uniprot ID | P14649 |
|---|---|
| Protein Name | Myosin light chain 6B |
| Gene Name | MYL6B |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 107 | PTNAEVLKVLGNPKS |
| 35 | GAPPAKTKAEPAVPQ |
Function
Regulatory light chain of myosin. Does not bind calcium
Protein Sequence
10
MPPKKDVPVK
20
KPAGPSISKP
30
AAKPAAAGAP
40
PAKTKAEPAV
50
PQAPQKTQEP
60
PVDLSKVVIE
70
FNKDQLEEFK
80
EAFELFDRVG
90
DGKILYSQCG
100
DVMRALGQNP
110
TNAEVLKVLG
120
NPKSDELKSR
130
RVDFETFLPM
140
LQAVAKNRGQ
150
GTYEDYLEGF
160
RVFDKEGNGK
170
VMGAELRHVL
180
TTLGEKMTEE
190
EVETVLAGHE
200
DSNGCINYEA
FLKHILSV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016461 | unconventional myosin complex |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0005859 | muscle myosin complex |
| Cellular Component | GO:0016459 | myosin complex |
| Cellular Component | GO:0016460 | myosin II complex |
| Molecular Function | GO:0005509 | calcium ion binding |
| Molecular Function | GO:0003774 | cytoskeletal motor activity |
| Molecular Function | GO:0000146 | microfilament motor activity |
| Molecular Function | GO:0008307 | structural constituent of muscle |
| Biological Process | GO:0006936 | muscle contraction |
| Biological Process | GO:0030049 | muscle filament sliding |
| Biological Process | GO:0007519 | skeletal muscle tissue development |
Reference
[1] Lin Y, Chen M, Wang D, Yu Y, Chen R et al.. Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.. J Proteome Res 22(6):1712-1722. 2023 Jun 2. PMID: 37159428.
[2] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.