Search Results
Overview
| Uniprot ID | P14668 |
|---|---|
| Protein Name | Annexin A5 |
| Gene Name | Anxa5 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 74 | MKSELTGKFEKLIVA |
| 99 | YELKHALKGAGTDEK |
Function
This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade
Protein Sequence
10
MALRGTVTDF
20
SGFDGRADAE
30
VLRKAMKGLG
40
TDEDSILNLL
50
TARSNAQRQQ
60
IAEEFKTLFG
70
RDLVNDMKSE
80
LTGKFEKLIV
90
ALMKPSRLYD
100
AYELKHALKG
110
AGTDEKVLTE
120
IIASRTPEEL
130
RAIKQAYEEE
140
YGSNLEDDVV
150
GDTSGYYQRM
160
LVVLLQANRD
170
PDTAIDDAQV
180
ELDAQALFQA
190
GELKWGTDEE
200
KFITILGTRS
210
VSHLRRVFDK
220
YMTISGFQIE
230
ETIDRETSGN
240
LENLLLAVVK
250
SIRSIPAYLA
260
ETLYYAMKGA
270
GTDDHTLIRV
280
IVSRSEIDLF
290
NIRKEFRKNF
300
ATSLYSMIKG
310
DTSGDYKKAL
LLLCGGEDD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030672 | synaptic vesicle membrane |
| Cellular Component | GO:0043679 | axon terminus |
| Cellular Component | GO:0042995 | cell projection |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0072563 | endothelial microparticle |
| Cellular Component | GO:0009897 | external side of plasma membrane |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0014704 | intercalated disc |
| Cellular Component | GO:0043025 | neuronal cell body |
| Cellular Component | GO:0043204 | perikaryon |
| Cellular Component | GO:0042383 | sarcolemma |
| Cellular Component | GO:0008021 | synaptic vesicle |
| Cellular Component | GO:0012506 | vesicle membrane |
| Cellular Component | GO:0030018 | Z disc |
| Molecular Function | GO:0005509 | calcium ion binding |
| Molecular Function | GO:0005544 | calcium-dependent phospholipid binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0005388 | P-type calcium transporter activity |
| Molecular Function | GO:0017046 | peptide hormone binding |
| Molecular Function | GO:0001786 | phosphatidylserine binding |
| Molecular Function | GO:0030971 | receptor tyrosine kinase binding |
| Biological Process | GO:0007596 | blood coagulation |
| Biological Process | GO:0097211 | cellular response to gonadotropin-releasing hormone |
| Biological Process | GO:0071284 | cellular response to lead ion |
| Biological Process | GO:0030195 | negative regulation of blood coagulation |
| Biological Process | GO:1902721 | negative regulation of prolactin secretion |
| Biological Process | GO:0043065 | positive regulation of apoptotic process |
| Biological Process | GO:1901317 | regulation of flagellated sperm motility |
| Biological Process | GO:0051592 | response to calcium ion |
| Biological Process | GO:0097066 | response to thyroid hormone |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.