Search Results
Overview
| Uniprot ID | P14669 |
|---|---|
| Protein Name | Annexin A3 |
| Gene Name | Anxa3 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 170 | GGRDESLKVDEHLAK |
| 178 | VDEHLAKKDAQTLYD |
| 189 | TLYDAGEKKWGTDED |
| 190 | LYDAGEKKWGTDEDK |
| 264 | GRLHQALKGAGTDEF |
| 33 | EAIRKAIKGIGTDEK |
| 40 | KGIGTDEKTLINILT |
Function
Inhibitor of phospholipase A2, also possesses anti-coagulant properties
Protein Sequence
10
MAASLWVGPR
20
GTINNYPGFN
30
PSVDAEAIRK
40
AIKGIGTDEK
50
TLINILTERS
60
NAQRQLIVKQ
70
YQEAYEQALK
80
ADLKGDLSGH
90
FEHVMVALIT
100
APAVFDAKQL
110
KKSMRGMGTD
120
EDTLIEILTT
130
RTSRQMKEIS
140
QAYYTAYKKN
150
LRDDISSETS
160
GDFRKALLTL
170
ADGGRDESLK
180
VDEHLAKKDA
190
QTLYDAGEKK
200
WGTDEDKFTE
210
ILCLRSFPQL
220
KLTFDEYRNI
230
SQKDIEDSIK
240
GELSGHFEDL
250
LLAVVRCTRN
260
TPAFLAGRLH
270
QALKGAGTDE
280
FTLNRIMVSR
290
SEIDLLDIRR
300
EFKKHYGCSL
310
YSAIQSDTSG
320
DYRTVLLKIC
GGDD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0043025 | neuronal cell body |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0030670 | phagocytic vesicle membrane |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0042581 | specific granule |
| Cellular Component | GO:0012506 | vesicle membrane |
| Molecular Function | GO:0005509 | calcium ion binding |
| Molecular Function | GO:0005544 | calcium-dependent phospholipid binding |
| Molecular Function | GO:0048306 | calcium-dependent protein binding |
| Molecular Function | GO:0001786 | phosphatidylserine binding |
| Molecular Function | GO:0019834 | phospholipase A2 inhibitor activity |
| Biological Process | GO:0031100 | animal organ regeneration |
| Biological Process | GO:0042742 | defense response to bacterium |
| Biological Process | GO:0021766 | hippocampus development |
| Biological Process | GO:0043312 | neutrophil degranulation |
| Biological Process | GO:0006909 | phagocytosis |
| Biological Process | GO:0045766 | positive regulation of angiogenesis |
| Biological Process | GO:0051054 | positive regulation of DNA metabolic process |
| Biological Process | GO:0010595 | positive regulation of endothelial cell migration |
| Biological Process | GO:0051384 | response to glucocorticoid |
| Biological Process | GO:0070848 | response to growth factor |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.