Search Results
Overview
| Uniprot ID | P15090 |
|---|---|
| Protein Name | Fatty acid-binding protein, adipocyte |
| Gene Name | FABP4 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 32 | GVGFATRKVAGMAKP |
Function
Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus
Protein Sequence
10
MCDAFVGTWK
20
LVSSENFDDY
30
MKEVGVGFAT
40
RKVAGMAKPN
50
MIISVNGDVI
60
TIKSESTFKN
70
TEISFILGQE
80
FDEVTADDRK
90
VKSTITLDGG
100
VLVHVQKWDG
110
KSTTIKRKRE
120
DDKLVVECVM
130
KGVTSTRVYE
RA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0005811 | lipid droplet |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0005504 | fatty acid binding |
| Molecular Function | GO:0051427 | hormone receptor binding |
| Molecular Function | GO:0060229 | lipase activator activity |
| Molecular Function | GO:0005319 | lipid transporter activity |
| Molecular Function | GO:0036041 | long-chain fatty acid binding |
| Molecular Function | GO:0005324 | long-chain fatty acid transmembrane transporter activity |
| Biological Process | GO:0015908 | fatty acid transport |
| Biological Process | GO:0015909 | long-chain fatty acid transport |
| Biological Process | GO:0120162 | positive regulation of cold-induced thermogenesis |
| Biological Process | GO:0019433 | triglyceride catabolic process |
| Biological Process | GO:0070343 | white fat cell proliferation |
Reference
[1] Lin Y, Chen M, Wang D, Yu Y, Chen R et al.. Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.. J Proteome Res 22(6):1712-1722. 2023 Jun 2. PMID: 37159428.