Search Results
Overview
| Uniprot ID | P15429 |
|---|---|
| Protein Name | Beta-enolase |
| Gene Name | Eno3 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 406 | CRSERLAKYNQLMRI |
Function
Enolase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in glycolysis and the reverse reaction in gluconeogenesis. Appears to have a function in striated muscle development and regeneration
Protein Sequence
10
MAMQKIFARE
20
ILDSRGNPTV
30
EVDLHTAKGR
40
FRAAVPSGAS
50
TGIYEALELR
60
DGDKSRYLGK
70
GVLKAVEHIN
80
KTLGPALLEK
90
KLSVVDQEKV
100
DKFMIELDGT
110
ENKSKFGANA
120
ILGVSLAVCK
130
AGAAEKGVPL
140
YRHIADLAGN
150
PDLVLPVPAF
160
NVINGGSHAG
170
NKLAMQEFMI
180
LPVGASSFKE
190
AMRIGAEVYH
200
HLKGVIKAKY
210
GKDATNVGDE
220
GGFAPNILEN
230
NEALELLKTA
240
IQAAGYPDKV
250
VIGMDVAASE
260
FYRNGKYDLD
270
FKSPDDPARH
280
ISGEKLGELY
290
KSFIKNYPVV
300
SIEDPFDQDD
310
WATWTSFLSG
320
VDIQIVGDDL
330
TVTNPKRIAQ
340
AVEKKACNCL
350
LLKVNQIGSV
360
TESIQACKLA
370
QSNGWGVMVS
380
HRSGETEDTF
390
IADLVVGLCT
400
GQIKTGAPCR
410
SERLAKYNQL
420
MRIEEALGDK
430
AVFAGRKFRN
PKAK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0000015 | phosphopyruvate hydratase complex |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0000287 | magnesium ion binding |
| Molecular Function | GO:0004634 | phosphopyruvate hydratase activity |
| Molecular Function | GO:0044877 | protein-containing complex binding |
| Biological Process | GO:0061621 | canonical glycolysis |
| Biological Process | GO:0006096 | glycolytic process |
| Biological Process | GO:0009410 | response to xenobiotic stimulus |
| Biological Process | GO:0043403 | skeletal muscle tissue regeneration |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.