Search Results
Overview
| Uniprot ID | P16930 |
|---|---|
| Protein Name | Fumarylacetoacetase |
| Gene Name | FAH |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 144 | VGIMFRDKENALMPN |
| 316 | SQAATICKSNFKYMY |
| 371 | ELSWKGTKPIDLGNG |
Function
No function data available.
Protein Sequence
10
MSFIPVAEDS
20
DFPIHNLPYG
30
VFSTRGDPRP
40
RIGVAIGDQI
50
LDLSIIKHLF
60
TGPVLSKHQD
70
VFNQPTLNSF
80
MGLGQAAWKE
90
ARVFLQNLLS
100
VSQARLRDDT
110
ELRKCAFISQ
120
ASATMHLPAT
130
IGDYTDFYSS
140
RQHATNVGIM
150
FRDKENALMP
160
NWLHLPVGYH
170
GRASSVVVSG
180
TPIRRPMGQM
190
KPDDSKPPVY
200
GACKLLDMEL
210
EMAFFVGPGN
220
RLGEPIPISK
230
AHEHIFGMVL
240
MNDWSARDIQ
250
KWEYVPLGPF
260
LGKSFGTTVS
270
PWVVPMDALM
280
PFAVPNPKQD
290
PRPLPYLCHD
300
EPYTFDINLS
310
VNLKGEGMSQ
320
AATICKSNFK
330
YMYWTMLQQL
340
THHSVNGCNL
350
RPGDLLASGT
360
ISGPEPENFG
370
SMLELSWKGT
380
KPIDLGNGQT
390
RKFLLDGDEV
400
IITGYCQGDG
410
YRIGFGQCAG
KVLPALLPS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0070062 | extracellular exosome |
| Molecular Function | GO:0004334 | fumarylacetoacetase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Biological Process | GO:1902000 | homogentisate catabolic process |
| Biological Process | GO:0006559 | L-phenylalanine catabolic process |
| Biological Process | GO:0006572 | L-tyrosine catabolic process |
| Biological Process | GO:0006629 | lipid metabolic process |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.