Search Results
Overview
| Uniprot ID | P17074 |
|---|---|
| Protein Name | Small ribosomal subunit protein eS19 |
| Gene Name | Rps19 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 115 | EGLKMVEKDQDGGRK |
| 122 | KDQDGGRKLTPQGQR |
| 143 | GQVAAANKKH***** |
| 29 | LKKSGKLKVPEWVDT |
| 38 | PEWVDTVKLAKHKEL |
| 43 | TVKLAKHKELAPYDE |
| 77 | AGVGSMTKIYGGRQR |
Function
Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Required for pre-rRNA processing and maturation of 40S ribosomal subunits. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity)
Protein Sequence
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0022626 | cytosolic ribosome |
| Cellular Component | GO:0022627 | cytosolic small ribosomal subunit |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0014069 | postsynaptic density |
| Cellular Component | GO:0005840 | ribosome |
| Cellular Component | GO:0015935 | small ribosomal subunit |
| Cellular Component | GO:0032040 | small-subunit processome |
| Cellular Component | GO:0045202 | synapse |
| Molecular Function | GO:0017134 | fibroblast growth factor binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0019901 | protein kinase binding |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0003735 | structural constituent of ribosome |
| Molecular Function | GO:0031369 | translation initiation factor binding |
| Biological Process | GO:0061844 | antimicrobial humoral immune response mediated by antimicrobial peptide |
| Biological Process | GO:0030218 | erythrocyte differentiation |
| Biological Process | GO:0030490 | maturation of SSU-rRNA |
| Biological Process | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| Biological Process | GO:0002548 | monocyte chemotaxis |
| Biological Process | GO:0060266 | negative regulation of respiratory burst involved in inflammatory response |
| Biological Process | GO:0007219 | Notch signaling pathway |
| Biological Process | GO:0007000 | nucleolus organization |
| Biological Process | GO:0060265 | positive regulation of respiratory burst involved in inflammatory response |
| Biological Process | GO:0000028 | ribosomal small subunit assembly |
| Biological Process | GO:0042274 | ribosomal small subunit biogenesis |
| Biological Process | GO:0006364 | rRNA processing |
| Biological Process | GO:0006412 | translation |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.