Search Results
Overview
| Uniprot ID | P19001 |
|---|---|
| Protein Name | Keratin, type I cytoskeletal 19 |
| Gene Name | Krt19 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 100 | RLASYLDKVRALEQA |
Function
Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle (By similarity)
Protein Sequence
10
MTSYSYRQTS
20
AMSSFGGTGG
30
GSVRIGSGGV
40
FRAPSIHGGS
50
GGRGVSVSST
60
RFVTSSSGSY
70
GGVRGGSFSG
80
TLAVSDGLLS
90
GNEKITMQNL
100
NDRLASYLDK
110
VRALEQANGE
120
LEVKIRDWYQ
130
KQGPGPSRDY
140
NHYFKTIEDL
150
RDKILGATID
160
NSKIVLQIDN
170
ARLAADDFRT
180
KFETEHALRL
190
SVEADINGLR
200
RVLDELTLAR
210
TDLEMQIESL
220
KEELAYLKKN
230
HEEEITALRS
240
QVGGQVSVEV
250
DSTPGVDLAK
260
ILSEMRSQYE
270
IMAEKNRKDA
280
EATYLARIEE
290
LNTQVAVHSE
300
QIQISKTEVT
310
DLRRTLQGLE
320
IELQSQLSMK
330
AALEGTLAET
340
EARYGVQLSQ
350
IQSVISGFEA
360
QLSDVRADIE
370
RQNQEYKQLM
380
DIKSRLEQEI
390
ATYRSLLEGQ
400
EAHYNNLPTP
KAI
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016327 | apicolateral plasma membrane |
| Cellular Component | GO:0071944 | cell periphery |
| Cellular Component | GO:0043034 | costamere |
| Cellular Component | GO:0005856 | cytoskeleton |
| Cellular Component | GO:0016010 | dystrophin-associated glycoprotein complex |
| Cellular Component | GO:0045111 | intermediate filament cytoskeleton |
| Cellular Component | GO:0045095 | keratin filament |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0042383 | sarcolemma |
| Cellular Component | GO:1990357 | terminal web |
| Cellular Component | GO:0030018 | Z disc |
| Molecular Function | GO:0044877 | protein-containing complex binding |
| Molecular Function | GO:0008307 | structural constituent of muscle |
| Molecular Function | GO:0030280 | structural constituent of skin epidermis |
| Biological Process | GO:0060706 | cell differentiation involved in embryonic placenta development |
| Biological Process | GO:0030855 | epithelial cell differentiation |
| Biological Process | GO:0045109 | intermediate filament organization |
| Biological Process | GO:0002009 | morphogenesis of an epithelium |
| Biological Process | GO:0007219 | Notch signaling pathway |
| Biological Process | GO:0043627 | response to estrogen |
| Biological Process | GO:0045214 | sarcomere organization |
Reference
[1] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.